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MORC2 sirna

Scan QR to view Datasheet Catalog #    MBS8211075 MORC2 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

MORC2 siRNA (Human)

 Product Synonym Names    KIAA0852; ZCWCC1; MORC family CW-type zinc finger protein 2; Zinc finger CW-type coiled-coil domain protein 1
 Product Gene Name   

MORC2 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9Y6X9
 Host    Synthetic
 Species Reactivity    Human
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 Specificity    MORC2 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human MORC2 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of MORC2 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MORC2 sirna

   siRNA to inhibit MORC2 expression using RNA interference
 Applications Tested/Suitable for MORC2 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for MORC2. It may not necessarily be applicable to this product.
 NCBI GI #    735997387
 NCBI GeneID    22880
 NCBI Accession #    NP_001290185.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001303256.1 [Other Products]
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 UniProt Primary Accession #    Q9Y6X9 [Other Products]
 UniProt Secondary Accession #    Q9UF28; Q9Y6V2; B2RNB1 [Other Products]
 UniProt Related Accession #    Q9Y6X9 [Other Products]
 Molecular Weight    110,724 Da
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 NCBI Official Full Name    MORC family CW-type zinc finger protein 2 isoform 1
 NCBI Official Synonym Full Names    MORC family CW-type zinc finger 2
 NCBI Official Symbol    MORC2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    MORC family CW-type zinc finger protein 2
 UniProt Protein Name    MORC family CW-type zinc finger protein 2
 UniProt Synonym Protein Names   
Zinc finger CW-type coiled-coil domain protein 1
 Protein Family    MORC family CW-type zinc finger protein
 UniProt Gene Name    MORC2 [Similar Products]
 UniProt Synonym Gene Names    KIAA0852; ZCWCC1 [Similar Products]
 UniProt Entry Name    MORC2_HUMAN
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 UniProt Comments for MORC2    MORC2: a protein containing a Zinc finger CW-type coiled-coil domain and a HATPase_c domain. HATPase_c domains are found in several ATP-binding proteins including histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, and DNA mismatch repair proteins.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: nucleoplasm; cytoplasm; nucleus; cytosol

Molecular Function: zinc ion binding

Biological Process: fatty acid metabolic process
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 Research Articles on MORC2    1. these results demonstrate a cytosolic function of MORC2 in lipogenesis, adipogenic differentiation, and lipid homeostasis by regulating the activity of ACLY.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MORC2 sirnaDiseases associated with MORC2 sirna
 Reference Product  PubMed Publications
 HDAC4 sirna  >1 publications with MORC2 and HDAC4
 CA9 sirna  >1 publications with MORC2 and CA9
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with MORC2 and Breast Neoplasms
Organs/Tissues associated with MORC2 sirna
 Organ/Tissue Name  Pubmed Publications
 Mammary Gland Antibodies  >1 publications with MORC2 and Mammary Gland
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