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NGRN sirna

Scan QR to view Datasheet Catalog #    MBS8204697 NGRN sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

NGRN siRNA (Human)

 Product Synonym Names    FI58G; Neugrin; Mesenchymal stem cell protein DSC92; Neurite outgrowth-associated protein; Spinal cord-derived protein FI58G
 Product Gene Name   

NGRN sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9NPE2
 Host    Synthetic
 Species Reactivity    Human
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 Specificity    NGRN siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human NGRN gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of NGRN sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for NGRN sirna

   siRNA to inhibit NGRN expression using RNA interference
 Applications Tested/Suitable for NGRN sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for NGRN. It may not necessarily be applicable to this product.
 NCBI GI #    75677385
 NCBI GeneID    51335
 NCBI Accession #    NP_001028260.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001033088.1 [Other Products]
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 UniProt Primary Accession #    Q9NPE2 [Other Products]
 UniProt Secondary Accession #    Q4V9L7; Q9HBL4; B2R6M8 [Other Products]
 UniProt Related Accession #    Q9NPE2 [Other Products]
 Molecular Weight    6,851 Da
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 NCBI Official Full Name    neugrin
 NCBI Official Synonym Full Names    neugrin, neurite outgrowth associated
 NCBI Official Symbol    NGRN [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    neugrin
 UniProt Protein Name    Neugrin
 UniProt Synonym Protein Names   
Mesenchymal stem cell protein DSC92; Neurite outgrowth-associated protein; Spinal cord-derived protein FI58G
 Protein Family    Neugrin
 UniProt Gene Name    NGRN [Similar Products]
 UniProt Synonym Gene Names    FI58G [Similar Products]
 UniProt Entry Name    NGRN_HUMAN
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 UniProt Comments for NGRN    NGRN: a neurite outgrowth associated protein and upregulated with neuronal differentiation in neuroblastoma cells.

Protein type: Secreted; Secreted, signal peptide; Cell development/differentiation; RNA-binding

Chromosomal Location of Human Ortholog: 15q26.1

Cellular Component: extracellular region; nucleus

Biological Process: neuron differentiation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with NGRN sirnaOrgans/Tissues associated with NGRN sirna
 Disease Name  Pubmed Publications
 Learning Disorders Antibodies  >1 publications with NGRN and Learning Disorders
 Nervous System Diseases Antibodies  >1 publications with NGRN and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with NGRN and Brain
 Liver Antibodies  >1 publications with NGRN and Liver
 Thyroid Antibodies  >1 publications with NGRN and Thyroid
 Heart Antibodies  >1 publications with NGRN and Heart
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