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ODAM sirna

Scan QR to view Datasheet Catalog #    MBS8207546 ODAM sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ODAM, siRNA

 Also Known As   

ODAM siRNA (Rat)

 Product Synonym Names    APIN; Odontogenic ameloblast-associated protein; Apin
 Product Gene Name   

ODAM sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q3HS83
 Host    Synthetic
 Species Reactivity    Rat
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 Specificity    ODAM siRNA (Rat) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of rat ODAM gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of ODAM sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for ODAM sirna

   siRNA to inhibit ODAM expression using RNA interference
 Applications Tested/Suitable for ODAM sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for ODAM. It may not necessarily be applicable to this product.
 NCBI GI #    112984154
 NCBI GeneID    641555
 NCBI Accession #    NP_001037739.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001044274.1 [Other Products]
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 UniProt Primary Accession #    Q3HS83 [Other Products]
 UniProt Related Accession #    Q3HS83 [Other Products]
 Molecular Weight    30,443 Da
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 NCBI Official Full Name    odontogenic ameloblast-associated protein
 NCBI Official Synonym Full Names    odontogenic, ameloblast asssociated
 NCBI Official Symbol    Odam [Similar Products]
 NCBI Official Synonym Symbols   
Apin
[Similar Products]
 NCBI Protein Information    odontogenic ameloblast-associated protein
 UniProt Protein Name    Odontogenic ameloblast-associated protein
 UniProt Synonym Protein Names   
Apin
 Protein Family    Odontogenic ameloblast-associated protein
 UniProt Gene Name    Odam [Similar Products]
 UniProt Synonym Gene Names    Apin [Similar Products]
 UniProt Entry Name    ODAM_RAT
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 UniProt Comments for ODAM    Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.
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 Research Articles on ODAM    1. ODAM and AMTN have a role at the cell-tooth interface, and that ODAM is likely also implicated in cellular events during formation and regeneration of the junctional epithelium.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ODAM sirnaOrgans/Tissues associated with ODAM sirna
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with ODAM and Breast Neoplasms
 Intestinal Diseases Antibodies  >1 publications with ODAM and Intestinal Diseases
 Neoplasm Metastasis Antibodies  >1 publications with ODAM and Neoplasm Metastasis
 Fibrosis Antibodies  >1 publications with ODAM and Fibrosis
 Hypertension Antibodies  >1 publications with ODAM and Hypertension
 Acute Kidney Injury Antibodies  >1 publications with ODAM and Acute Kidney Injury
 Inflammation Antibodies  >1 publications with ODAM and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Tooth Antibodies  >19 publications with ODAM and Tooth
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