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OSTF1 sirna

Scan QR to view Datasheet Catalog #    MBS829210 OSTF1 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

OSTF1 siRNA (Mouse)

 Product Synonym Names    SH3D3; SH3P2; Osteoclast-stimulating factor 1; SH3 domain protein 3
 Product Gene Name   

OSTF1 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q62422
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    OSTF1 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse OSTF1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of OSTF1 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for OSTF1 sirna

   siRNA to inhibit OSTF1 expression using RNA interference
 Applications Tested/Suitable for OSTF1 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for OSTF1. It may not necessarily be applicable to this product.
 NCBI GI #    22267440
 NCBI GeneID    20409
 NCBI Accession #    NP_059071.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017375.3 [Other Products]
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 UniProt Primary Accession #    Q62422 [Other Products]
 UniProt Secondary Accession #    Q3UF05 [Other Products]
 UniProt Related Accession #    Q62422 [Other Products]
 Molecular Weight    23,783 Da
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 NCBI Official Full Name    osteoclast-stimulating factor 1
 NCBI Official Synonym Full Names    osteoclast stimulating factor 1
 NCBI Official Symbol    Ostf1 [Similar Products]
 NCBI Official Synonym Symbols   
SH3P2; Sh3d3; C78236
[Similar Products]
 NCBI Protein Information    osteoclast-stimulating factor 1
 UniProt Protein Name    Osteoclast-stimulating factor 1
 UniProt Synonym Protein Names   
SH3 domain protein 3
 Protein Family    Osteoclast-stimulating factor
 UniProt Gene Name    Ostf1 [Similar Products]
 UniProt Synonym Gene Names    Sh3d3; Sh3p2 [Similar Products]
 UniProt Entry Name    OSTF1_MOUSE
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 UniProt Comments for OSTF1    OSTF1: Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Cellular Component: cytoplasm

Molecular Function: SH3 domain binding
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 Research Articles on OSTF1    1. SH3P2, a novel component of adhesion sites, is involved in Cbl and Src-mediated pathways
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OSTF1 sirnaDiseases associated with OSTF1 sirna
 Reference Product  PubMed Publications
 Tsc22d4 sirna  >1 publications with OSTF1 and Tsc22d4
 Tsc22d2 sirna  >1 publications with OSTF1 and Tsc22d2
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >2 publications with OSTF1 and Congenital Abnormalities
 Obesity Antibodies  >2 publications with OSTF1 and Obesity
 Atrophy Antibodies  >2 publications with OSTF1 and Atrophy
 Inflammation Antibodies  >2 publications with OSTF1 and Inflammation
 Necrosis Antibodies  >2 publications with OSTF1 and Necrosis
 Abnormalities, Multiple Antibodies  >1 publications with OSTF1 and Abnormalities, Multiple
 Infertility, Male Antibodies  >1 publications with OSTF1 and Infertility, Male
 Neoplasm Metastasis Antibodies  >1 publications with OSTF1 and Neoplasm Metastasis
 Kidney Diseases Antibodies  >1 publications with OSTF1 and Kidney Diseases
Organs/Tissues associated with OSTF1 sirna
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >20 publications with OSTF1 and Bone
 Bone Marrow Antibodies  >9 publications with OSTF1 and Bone Marrow
 Blood Antibodies  >7 publications with OSTF1 and Blood
 Connective Tissue Antibodies  >4 publications with OSTF1 and Connective Tissue
 Kidney Antibodies  >4 publications with OSTF1 and Kidney
 Brain Antibodies  >3 publications with OSTF1 and Brain
 Intestine Antibodies  >2 publications with OSTF1 and Intestine
 Skin Antibodies  >1 publications with OSTF1 and Skin
 Testis Antibodies  >1 publications with OSTF1 and Testis
 Liver Antibodies  >1 publications with OSTF1 and Liver
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