NP_036750.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
11,776 Da
NCBI Official Full Name
protein S100-A4
NCBI Official Synonym Full Names
S100 calcium-binding protein A4
NCBI Official Synonym Symbols
42A; 18A2; CAPL; MTS1; P9ka; PEL98; RNP9KA [Similar Products]
NCBI Protein Information
protein S100-A4
UniProt Protein Name
Protein S100-A4
UniProt Synonym Protein Names
Metastasin; Nerve growth factor-induced protein 42A; P9K; Placental calcium-binding protein; S100 calcium-binding protein A4
UniProt Entry Name
S10A4_RAT
NCBI Summary for S100A4
may play a role in regulation of cell growth and differentiation [RGD, Feb 2006]
UniProt Comments for S100A4
S100A4: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Protein type: Calcium-binding; Motility/polarity/chemotaxis
Cellular Component: extracellular space; neuron projection; perinuclear region of cytoplasm; nucleus
Molecular Function: identical protein binding; RAGE receptor binding; protein binding; protein homodimerization activity; protein heterodimerization activity; calcium ion binding; actin binding; calcium-dependent protein binding
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade
Research Articles on S100A4
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Organs/Tissues associated with S100A4 sirna
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