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SRPX sirna

Scan QR to view Datasheet Catalog #    MBS8231155 SRPX sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SRPX, siRNA

 Also Known As   

SRPX siRNA (Rat)

 Product Synonym Names    DRS; Sushi repeat-containing protein SRPX; Down-regulated by v-SRC; DRS
 Product Gene Name   

SRPX sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q63769
 Host    Synthetic
 Species Reactivity    Rat
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 Specificity    SRPX siRNA (Rat) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of rat SRPX gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of SRPX sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for SRPX sirna

   siRNA to inhibit SRPX expression using RNA interference
 Applications Tested/Suitable for SRPX sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for SRPX. It may not necessarily be applicable to this product.
 NCBI GI #    11993952
 NCBI GeneID    64316
 NCBI Accession #    NP_071969.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022524.1 [Other Products]
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 UniProt Primary Accession #    Q63769 [Other Products]
 UniProt Secondary Accession #    Q5PPK5 [Other Products]
 UniProt Related Accession #    Q63769 [Other Products]
 Molecular Weight    49,442 Da
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 NCBI Official Full Name    sushi repeat-containing protein SRPX
 NCBI Official Synonym Full Names    sushi-repeat-containing protein, X-linked
 NCBI Official Symbol    Srpx [Similar Products]
 NCBI Official Synonym Symbols   
Drs
[Similar Products]
 NCBI Protein Information    sushi repeat-containing protein SRPX
 UniProt Protein Name    Sushi repeat-containing protein SRPX
 UniProt Synonym Protein Names   
Down-regulated by v-SRC; DRS
 Protein Family    Sushi repeat-containing protein
 UniProt Gene Name    Srpx [Similar Products]
 UniProt Synonym Gene Names    Drs; DRS [Similar Products]
 UniProt Entry Name    SRPX_RAT
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 NCBI Summary for SRPX    expression is suppressed in cells transformed by v-src and other oncogenes, however expression is not suppressed in HPV type 16 E6E7 or polyomavirus large T transformed cells [RGD, Jan 2010]
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 Research Articles on SRPX    1. expression of drs mRNA in well-differentiated, moderately differentiated, and poorly differentiated lung adenocarcinoma tissues (drs; down-regulated by v-scr)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with SRPX sirnaOrgans/Tissues associated with SRPX sirna
 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >8 publications with SRPX and Cell Transformation, Neoplastic
 Adenocarcinoma Antibodies  >7 publications with SRPX and Adenocarcinoma
 Lung Neoplasms Antibodies  >3 publications with SRPX and Lung Neoplasms
 Liver Diseases Antibodies  >1 publications with SRPX and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with SRPX and Liver Neoplasms
 Pancreatic Neoplasms Antibodies  >1 publications with SRPX and Pancreatic Neoplasms
 Cognition Disorders Antibodies  >1 publications with SRPX and Cognition Disorders
 Carcinoma, Hepatocellular Antibodies  >1 publications with SRPX and Carcinoma, Hepatocellular
 Atrophy Antibodies  >1 publications with SRPX and Atrophy
 Cardiovascular Diseases Antibodies  >1 publications with SRPX and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >5 publications with SRPX and Ovary
 Liver Antibodies  >1 publications with SRPX and Liver
 Heart Antibodies  >1 publications with SRPX and Heart
 Connective Tissue Antibodies  >1 publications with SRPX and Connective Tissue
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