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STAMBP sirna

Scan QR to view Datasheet Catalog #    MBS8221551 STAMBP sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

STAMBP siRNA (Mouse)

 Product Synonym Names    AMSH; STAM-binding protein; Associated molecule with the SH3 domain of STAM
 Product Gene Name   

STAMBP sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9CQ26
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    STAMBP siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse STAMBP gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of STAMBP sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for STAMBP sirna

   siRNA to inhibit STAMBP expression using RNA interference
 Applications Tested/Suitable for STAMBP sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for STAMBP. It may not necessarily be applicable to this product.
 NCBI GI #    17941277
 NCBI GeneID    70527
 NCBI Accession #    NP_077201.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_024239.2 [Other Products]
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 UniProt Primary Accession #    Q9CQ26 [Other Products]
 UniProt Secondary Accession #    Q3UTI9 [Other Products]
 UniProt Related Accession #    Q9CQ26 [Other Products]
 Molecular Weight    48,514 Da
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 NCBI Official Full Name    STAM-binding protein
 NCBI Official Synonym Full Names    STAM binding protein
 NCBI Official Symbol    Stambp [Similar Products]
 NCBI Official Synonym Symbols   
Amsh; AW107289; mKIAA4198; 5330424L14Rik; 5730422L11Rik
[Similar Products]
 NCBI Protein Information    STAM-binding protein
 UniProt Protein Name    STAM-binding protein
 UniProt Synonym Protein Names   
Associated molecule with the SH3 domain of STAM
 Protein Family    STAM-binding protein
 UniProt Gene Name    Stambp [Similar Products]
 UniProt Synonym Gene Names    Amsh [Similar Products]
 UniProt Entry Name    STABP_MOUSE
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 UniProt Comments for STAMBP    AMSH: an adaptor protein involved in cytokine signal transduction the JAK-STAT cascade. Binds to the SH3 domain of the signal-transducing adaptor molecule STAM (signal transducing adaptor molecule). May play a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression.

Protein type: EC 3.4.19.-; Protease; EC; Ubiquitin-specific protease

Cellular Component: nucleoplasm; membrane; cytoplasm; plasma membrane; nucleus; endosome; cleavage furrow

Molecular Function: peptidase activity; protein domain specific binding; metallopeptidase activity; hydrolase activity; metal ion binding; ubiquitin-specific protease activity; pyroglutamyl-peptidase activity

Biological Process: protein deubiquitination; cytokinesis after mitosis; negative regulation of Ras protein signal transduction; negative regulation of neuron apoptosis; proteolysis; negative regulation of phosphoinositide 3-kinase cascade
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 Research Articles on STAMBP    1. These data suggest that AMSH plays an important role in degrading ubiquitinated proteins and glutamate receptors in vivo
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with STAMBP sirnaPathways associated with STAMBP sirna
 Reference Product  PubMed Publications
 Stam sirna  >21 publications with STAMBP and Stam
 Usp8 sirna  >8 publications with STAMBP and Usp8
 Chmp3 sirna  >6 publications with STAMBP and Chmp3
 Grb2 sirna  >2 publications with STAMBP and Grb2
 Chmp1b sirna  >2 publications with STAMBP and Chmp1b
 Smad6 sirna  >1 publications with STAMBP and Smad6
 Stam2 sirna  >1 publications with STAMBP and Stam2
 Products by Pathway  Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
Diseases associated with STAMBP sirnaOrgans/Tissues associated with STAMBP sirna
 Disease Name  Pubmed Publications
 Microcephaly Antibodies  >5 publications with STAMBP and Microcephaly
 Epilepsy Antibodies  >3 publications with STAMBP and Epilepsy
 Brain Diseases Antibodies  >2 publications with STAMBP and Brain Diseases
 Vascular Diseases Antibodies  >1 publications with STAMBP and Vascular Diseases
 Weight Gain Antibodies  >1 publications with STAMBP and Weight Gain
 Developmental Disabilities Antibodies  >1 publications with STAMBP and Developmental Disabilities
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with STAMBP and Brain
 Skin Antibodies  >2 publications with STAMBP and Skin
 Testis Antibodies  >1 publications with STAMBP and Testis
 Embryonic Tissue Antibodies  >1 publications with STAMBP and Embryonic Tissue
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