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TAPT1 sirna

Scan QR to view Datasheet Catalog #    MBS8212329 TAPT1 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TAPT1, siRNA

 Also Known As   

TAPT1 siRNA (Mouse)

 Product Synonym Names    Transmembrane anterior posterior transformation protein 1
 Product Gene Name   

TAPT1 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q4VBD2
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    TAPT1 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse TAPT1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of TAPT1 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TAPT1 sirna

   siRNA to inhibit TAPT1 expression using RNA interference
 Applications Tested/Suitable for TAPT1 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for TAPT1. It may not necessarily be applicable to this product.
 NCBI GI #    71143116
 NCBI GeneID    231225
 NCBI Accession #    NP_776125.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_173764.3 [Other Products]
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 UniProt Primary Accession #    Q4VBD2 [Other Products]
 UniProt Secondary Accession #    Q8CDI4 [Other Products]
 UniProt Related Accession #    Q4VBD2 [Other Products]
 Molecular Weight    63,894 Da
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 NCBI Official Full Name    transmembrane anterior posterior transformation protein 1
 NCBI Official Synonym Full Names    transmembrane anterior posterior transformation 1
 NCBI Official Symbol    Tapt1 [Similar Products]
 NCBI Official Synonym Symbols   
4932414K18Rik
[Similar Products]
 NCBI Protein Information    transmembrane anterior posterior transformation protein 1
 UniProt Protein Name    Transmembrane anterior posterior transformation protein 1
 Protein Family    Transmembrane anterior posterior transformation protein
 UniProt Gene Name    Tapt1 [Similar Products]
 UniProt Entry Name    TAPT1_MOUSE
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 UniProt Comments for TAPT1    TAPT1: May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development. In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169. Belongs to the TAPT1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: membrane; integral to membrane

Biological Process: in utero embryonic development; multicellular organismal development; embryonic skeletal development; post-embryonic development
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 Research Articles on TAPT1    1. TAPT1 is a downstream effector of HOXC8 that may act by transducing or transmitting extracellular information required for axial skeletal patterning during development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TAPT1 sirnaOrgans/Tissues associated with TAPT1 sirna
 Reference Product  PubMed Publications
 Nsun7 sirna  >1 publications with TAPT1 and Nsun7
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with TAPT1 and Bone
 Muscle Antibodies  >1 publications with TAPT1 and Muscle
 Embryonic Tissue Antibodies  >1 publications with TAPT1 and Embryonic Tissue
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