NP_001029174.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,494 Da
NCBI Official Full Name
transcriptional coactivator YAP1
NCBI Official Synonym Full Names
yes-associated protein 1
NCBI Official Synonym Symbols
NCBI Protein Information
transcriptional coactivator YAP1
UniProt Protein Name
Transcriptional coactivator YAP1
UniProt Synonym Protein Names
Protein yorkie homolog; Yes-associated protein YAP65 homolog
UniProt Synonym Gene Names
UniProt Entry Name
YAP1_RAT
UniProt Comments for YAP1
YAP1: an adaptor protein that binds to HER4 and the SH3 domain of the Yes tyrosine kinase. Associates with multiple transcription factors in the nucleus, and appears to be a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. Contains a WW domain that is found in various structural, regulatory and signaling molecules.
Protein type: Oncoprotein; Transcription, coactivator/corepressor
Cellular Component: nucleoplasm; transcription factor complex; membrane; cytoplasm; cell junction; cytosol; nucleus
Molecular Function: protein C-terminus binding; transcription coactivator activity; chromatin binding; transcription corepressor activity
Biological Process: paraxial mesoderm development; transcription from RNA polymerase II promoter; DNA damage induced protein phosphorylation; transcription, DNA-dependent; somatic stem cell maintenance; lateral mesoderm development; cell morphogenesis; negative regulation of epithelial cell differentiation; notochord development; positive regulation of organ growth; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; keratinocyte differentiation; cell proliferation; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis; response to DNA damage stimulus
Research Articles on YAP1
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Pathways associated with YAP1 sirna
Diseases associated with YAP1 sirna
Organs/Tissues associated with YAP1 sirna
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