Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow siRNA rightarrow YWHAH  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • FLT4 - VEGFR3 Antibody
 • SLC20A1 Antibody
 • growth hormone 2 (GH2) ELISA Kit
 • anaphase promoting complex subunit 5 (ANAPC5) ELISA Kit
 • RuBisCO Antibody
 • ERK1 + ERK2 (ERK1 - ERK2) Antibody
 • CD8a Antibody
 • CD29 Antibody
 • Lck Antibody
 • ALDH2 Antibody
 • bromodomain and PHD finger containing, 1 (BRPF1) ELISA Kit
 • Billverdin Reductase Antibody
 • CD90 Antibody
 • Janus Kinase (JK) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

YWHAH sirna

Scan QR to view Datasheet Catalog #    MBS8231385 YWHAH sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

YWHAH, siRNA

 Also Known As   

YWHAH siRNA (Human)

 Product Synonym Names    YWHA1; 14-3-3 protein eta; Protein AS1
 Product Gene Name   

YWHAH sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    113508
 3D Structure    ModBase 3D Structure for Q04917
Section Bar
 Host    Synthetic
 Species Reactivity    Human
Section Bar
 Specificity    YWHAH siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
Section Bar
 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human YWHAH gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of YWHAH sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for YWHAH sirna

   siRNA to inhibit YWHAH expression using RNA interference
 Applications Tested/Suitable for YWHAH sirna   

RNA Interference (RNAi)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for YWHAH. It may not necessarily be applicable to this product.
 NCBI GI #    4507951
 NCBI GeneID    7533
 NCBI Accession #    NP_003396.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003405.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q04917 [Other Products]
 UniProt Related Accession #    Q04917 [Other Products]
 Molecular Weight    28,219 Da
Table BarTOPTable Bar
 NCBI Official Full Name    14-3-3 protein eta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
 NCBI Official Symbol    YWHAH [Similar Products]
 NCBI Official Synonym Symbols   
YWHA1
[Similar Products]
 NCBI Protein Information    14-3-3 protein eta
 UniProt Protein Name    14-3-3 protein eta
 UniProt Synonym Protein Names   
Protein AS1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAH [Similar Products]
 UniProt Synonym Gene Names    YWHA1 [Similar Products]
 UniProt Entry Name    1433F_HUMAN
Section Bar
 NCBI Summary for YWHAH    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
Section Bar
 UniProt Comments for YWHAH    14-3-3 eta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes.

Protein type: Adaptor/scaffold; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: cytoplasmic vesicle membrane; cytoplasm; plasma membrane; cytosol

Molecular Function: insulin-like growth factor receptor binding; protein domain specific binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding

Biological Process: intracellular protein transport; substantia nigra development; apoptosis; regulation of neuron differentiation; glucocorticoid receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of synaptic plasticity; glucocorticoid catabolic process; negative regulation of dendrite morphogenesis; regulation of sodium ion transport
Table BarTOPTable Bar
 Research Articles on YWHAH    1. This study identified YWHAH significantly associated loci with a biologically plausible role in schizophrenia.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with YWHAH sirnaPathways associated with YWHAH sirna
 Reference Product  PubMed Publications
 YWHAE sirna  >2 publications with YWHAH and YWHAE
 FOXO3 sirna  >1 publications with YWHAH and FOXO3
 CDC25C sirna  >1 publications with YWHAH and CDC25C
 CDC25B sirna  >1 publications with YWHAH and CDC25B
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with YWHAH sirnaOrgans/Tissues associated with YWHAH sirna
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with YWHAH and Nervous System Diseases
 Brain Diseases Antibodies  >7 publications with YWHAH and Brain Diseases
 Insulin Resistance Antibodies  >1 publications with YWHAH and Insulin Resistance
 Carcinoma, Hepatocellular Antibodies  >1 publications with YWHAH and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with YWHAH and Liver Diseases
 Hypertrophy Antibodies  >1 publications with YWHAH and Hypertrophy
 Neoplasms, Experimental Antibodies  >1 publications with YWHAH and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with YWHAH and Liver Neoplasms
 Hyperplasia Antibodies  >1 publications with YWHAH and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with YWHAH and Brain
 Blood Antibodies  >3 publications with YWHAH and Blood
 Bone Antibodies  >3 publications with YWHAH and Bone
 Liver Antibodies  >2 publications with YWHAH and Liver
 Lymph Antibodies  >2 publications with YWHAH and Lymph
 Bone Marrow Antibodies  >2 publications with YWHAH and Bone Marrow
 Lung Antibodies  >2 publications with YWHAH and Lung
 Lymph Node Antibodies  >2 publications with YWHAH and Lymph Node
 Heart Antibodies  >1 publications with YWHAH and Heart
 Vascular Antibodies  >1 publications with YWHAH and Vascular
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions