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Myelin Basic Protein Brain, lyophilized Protein

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Catalog # MBS635008
Unit / Price
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  1 mg  /  $595 +1 FREE 8GB USB
Myelin Basic Protein Brain, lyophilized protein
Product Name

Myelin Basic Protein Brain, lyophilized, Protein

Popular Item
Full Product Name

Myelin Basic Protein, Human Brain, lyophilized (MBP)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
Human brain
Purity/Purification
>95% (SDS-PAGE)
Form/Format
Supplied as a lyophilized powder. No preservatives added. Reconstitute with 10mM HCl.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with with 10mM HCl. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of Myelin Basic Protein Brain, lyophilized protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Myelin Basic Protein Brain, lyophilized protein
In vitro, myelin basic protein (MBP) is a substrate for phosphorylation by several different protein kinases including MAPK, PKA, calmodulin-dependent protein kinase, PKC and phosphorylase kinase. Even highly specific protein kinases such as Raf1, MEK and MEKK can utilize MBP as an alternative substrate. Myelin basic protein (MBP) is a single-chain, flexible polypeptide of about 18.5kD existing in its natural environment as an extrinsic and loosely bound component of the cytoplasmic portion of the myelin membrane sandwich. Ultrastructural immunocytochemistry with anti-myelin basic protein has shown that MBP is localized in the compact myelin sheath. MBP has not been demonstrated in rough endoplasmic reticulum, lysosomes or any other cytoplasmic organelles. MBP serves as a marker for oligodendrocytes and Schwann cells. MBP is also a marker for malignant schwannomas and appears to play a significant role in the etiology of multiple sclerosis and experimental autoimmune encephalomyelitis.
Applications Tested/Suitable for Myelin Basic Protein Brain, lyophilized protein
ELISA (EL/EIA)
Suitable for use in ELISA or for antigen applications in immunological protocols. Immunoreactivity is verified using polyclonal and monoclonal antibodies against MBP.
Other applications not tested.
Molecular Weight
MBP contains 14.2kD (13.0 minor) and 18.5kD (17.2 minor) isoforms as well as their dimers (13.5% SDS-PAGE, non-reducing conditions).[Similar Products]
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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