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Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity).
Below are the list of possible A disintegrin and metalloproteinase with thrombospondin motifs products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications. |
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A disintegrin and metalloproteinase with thrombospondin motifs 18 ELISA Kit A disintegrin and metalloproteinase with thrombospondin motifs 18 Recombinant A disintegrin and metalloproteinase with thrombospondin motifs 18 Antibody | Also known as A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18). ADAMTS18: Defects in ADAMTS18 are the cause of Knobloch syndrome type 2 (KNO2). A developmental disorder primarily characterized by typical eye abnormalities, including high myopia, cataracts, dislocated lens, vitreoretinal degeneration, and retinal detachment, with occipital sk >>> ull defects, which can range from occipital encephalocele to occult cutis aplasia. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.24.-; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 16q23
Biological Process: eye development
Disease: Microcornea, Myopic Chorioretinal Atrophy, And Telecanthus |
ADAMTS18 ELISA Kit ADAMTS18 Recombinant ADAMTS18 Antibody | ADAMTS21 ELISA Kit ADAMTS21 Recombinant ADAMTS21 Antibody |
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A disintegrin and metalloproteinase with thrombospondin motifs 2 ELISA Kit A disintegrin and metalloproteinase with thrombospondin motifs 2 Recombinant A disintegrin and metalloproteinase with thrombospondin motifs 2 Antibody | Also known as A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI). ADAMTS2: Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in developme >>> nt that is independent of its role in collagen biosynthesis. Defects in ADAMTS2 are the cause of Ehlers-Danlos syndrome type 7C (EDS7C). EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS7C is marked by extremely fragile tissues, hyperextensible skin and easy bruising. Facial skin contains numerous folds, as in the cutis laxa syndrome. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.24.14; Extracellular matrix; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide
Cellular Component: proteinaceous extracellular matrix
Molecular Function: peptidase activity
Biological Process: collagen fibril organization; lung development; protein processing; skin development; spermatogenesis |
Adamts2 ELISA Kit Adamts2 Recombinant Adamts2 Antibody |
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