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Abnormal spindle-like microcephaly-associated protein

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Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis.

Below are the list of possible Abnormal spindle-like microcephaly-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Abnormal spindle-like microcephaly-associated protein

 Abnormal spindle-like microcephaly-associated protein ELISA Kit
 Abnormal spindle-like microcephaly-associated protein Recombinant
 Abnormal spindle-like microcephaly-associated protein Antibody
Also known as Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).
ASPM: Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis. Defects in ASPM are the cause of microcephaly primary type 5 (MCPH5); also known as true microcephaly or microcephaly vera. Microceph
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aly is defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits. This entity is inherited as autosomal recessive trait. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 1q31

Cellular Component: nucleus

Biological Process: spindle localization; spindle organization and biogenesis

Disease: Microcephaly 5, Primary, Autosomal Recessive
 ASPM ELISA Kit
 ASPM Recombinant
 ASPM Antibody
 MCPH5 ELISA Kit
 MCPH5 Recombinant
 MCPH5 Antibody
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Abnormal spindle-like microcephaly-associated protein homolog

 Abnormal spindle-like microcephaly-associated protein homolog ELISA Kit
 Abnormal spindle-like microcephaly-associated protein homolog Recombinant
 Abnormal spindle-like microcephaly-associated protein homolog Antibody
Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis ().
 ASPM ELISA Kit
 ASPM Recombinant
 ASPM Antibody
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