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Acid-sensing ion channel

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Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions.

Below are the list of possible Acid-sensing ion channel products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Acid-sensing ion channel 1

 Acid-sensing ion channel 1 ELISA Kit
 Acid-sensing ion channel 1 Recombinant
 Acid-sensing ion channel 1 Antibody
Also known as Acid-sensing ion channel 1 (ASIC1) (Acid-sensing ion channel 1.1) (Amiloride-sensitive cation channel 2-A, neuronal) (ZASIC1.1).
Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also tran
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sport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions.
 asic1 ELISA Kit
 asic1 Recombinant
 asic1 Antibody
 accn2a ELISA Kit
 accn2a Recombinant
 accn2a Antibody
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Acid-sensing ion channel 2

 Acid-sensing ion channel 2 ELISA Kit
 Acid-sensing ion channel 2 Recombinant
 Acid-sensing ion channel 2 Antibody
Also known as Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive brain sodium channel 2) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG).
ASIC2: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems
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to modulate. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Channel, cation; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Cellular Component: cell soma; dendritic spine; integral to membrane; integral to plasma membrane; neuron projection; synapse

Molecular Function: amiloride-sensitive sodium channel activity; cation channel activity; ion channel activity; ion gated channel activity; voltage-gated sodium channel activity

Biological Process: cation transport; detection of mechanical stimulus involved in sensory perception; negative regulation of apoptosis; phototransduction; positive regulation of synaptogenesis; regulation of blood coagulation; regulation of gene expression; regulation of membrane potential; regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback; regulation of vasoconstriction; response to acidity; response to mechanical stimulus; sensory perception of sound; sensory perception of sour taste; sodium ion transport
 Asic2 ELISA Kit
 Asic2 Recombinant
 Asic2 Antibody
 Accn1 ELISA Kit
 Accn1 Recombinant
 Accn1 Antibody
 Bnac1 ELISA Kit
 Bnac1 Recombinant
 Bnac1 Antibody
 Mdeg ELISA Kit
 Mdeg Recombinant
 Mdeg Antibody
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Acid-sensing ion channel 3

 Acid-sensing ion channel 3 ELISA Kit
 Acid-sensing ion channel 3 Recombinant
 Acid-sensing ion channel 3 Antibody
Also known as Acid-sensing ion channel 3 (ASIC3) (Amiloride-sensitive cation channel 3) (Dorsal root ASIC) (DRASIC).
ASIC3: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties. Bel
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ongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC3 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Cellular Component: integral to plasma membrane

Molecular Function: amiloride-sensitive sodium channel activity; cation channel activity; enterobactin transporter activity; PDZ domain binding; protein binding

Biological Process: cation transport; detection of chemical stimulus involved in sensory perception; detection of chemical stimulus involved in sensory perception of pain; detection of mechanical stimulus involved in sensory perception; detection of mechanical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception; detection of temperature stimulus involved in sensory perception of pain; response to acidity; response to heat; response to mechanical stimulus; sensory perception of sour taste; sodium ion transport
 Asic3 ELISA Kit
 Asic3 Recombinant
 Asic3 Antibody
 Accn3 ELISA Kit
 Accn3 Recombinant
 Accn3 Antibody
 Drasic ELISA Kit
 Drasic Recombinant
 Drasic Antibody
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Acid-sensing ion channel 4

 Acid-sensing ion channel 4 ELISA Kit
 Acid-sensing ion channel 4 Recombinant
 Acid-sensing ion channel 4 Antibody
Also known as Acid-sensing ion channel 4 (ASIC4) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1).
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride.
 asic4 ELISA Kit
 asic4 Recombinant
 asic4 Antibody
 accn4a ELISA Kit
 accn4a Recombinant
 accn4a Antibody
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Acid-sensing ion channel 5

 Acid-sensing ion channel 5 ELISA Kit
 Acid-sensing ion channel 5 Recombinant
 Acid-sensing ion channel 5 Antibody
Also known as Acid-sensing ion channel 5 (ASIC5) (Amiloride-sensitive cation channel 5) (Brain-liver-intestine amiloride-sensitive Na(+) channel) (BLINaC).
ASIC5: Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC5 subfamily.

Protein type: Channel, sodium; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Cellular Component: membra
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ne

Molecular Function: amiloride-sensitive sodium channel activity; hydrogen ion channel activity; sodium channel activity
 Asic5 ELISA Kit
 Asic5 Recombinant
 Asic5 Antibody
 Accn5 ELISA Kit
 Accn5 Recombinant
 Accn5 Antibody
 Blinac ELISA Kit
 Blinac Recombinant
 Blinac Antibody
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