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Activated RNA polymerase II transcriptional coactivator

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General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).

Below are the list of possible Activated RNA polymerase II transcriptional coactivator products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Activated RNA polymerase II transcriptional coactivator p15

 Activated RNA polymerase II transcriptional coactivator p15 ELISA Kit
 Activated RNA polymerase II transcriptional coactivator p15 Recombinant
 Activated RNA polymerase II transcriptional coactivator p15 Antibody
Also known as Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14).
PC4: a transcriptional coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, nonspecifically to double-stranded DNA (ds DNA). Interacts with CSTF2. Its activity is controlled by phosphorylation of the regulatory domain. Phosphorylation inactivates
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both dsDNA-binding and cofactor function. Seems to be phosphorylated in vivo by CK2 in at least 7 sites in the N-terminal Ser-rich region.

Protein type: DNA-binding; Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Cellular Component: nucleolus; nucleus; transcription factor complex

Molecular Function: single-stranded DNA binding; transcription coactivator activity

Biological Process: regulation of transcription from RNA polymerase II promoter
 Sub1 ELISA Kit
 Sub1 Recombinant
 Sub1 Antibody
 Pc4 ELISA Kit
 Pc4 Recombinant
 Pc4 Antibody
 Rpo2tc1 ELISA Kit
 Rpo2tc1 Recombinant
 Rpo2tc1 Antibody
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