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Activating signal cointegrator

Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation .

Below are the list of possible Activating signal cointegrator products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Activating signal cointegrator 1

 Activating signal cointegrator 1 ELISA Kit
 Activating signal cointegrator 1 Recombinant
 Activating signal cointegrator 1 Antibody
Also known as Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4).
TRIP4: thyroid receptor interacting protein 4 is a transcription coactivator of nuclear receptors including thyroid hormone receptor. Functions in conjunction with CBP-p300 and SRC-1. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as
a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: cytoplasm; neuromuscular junction; nucleoplasm; nucleus

Molecular Function: estrogen receptor binding; histone acetyltransferase binding; ligand-dependent nuclear receptor binding; protease binding; protein binding; transcription coactivator activity

Biological Process: estrogen receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of myoblast differentiation; regulation of transcription, DNA-dependent

Disease: Muscular Dystrophy, Congenital, Davignon-chauveau Type; Spinal Muscular Atrophy With Congenital Bone Fractures 1
 TRIP4 Recombinant
 TRIP4 Antibody
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