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Activating transcription factor 7-interacting protein

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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). May have ATPase activity.

Below are the list of possible Activating transcription factor 7-interacting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Activating transcription factor 7-interacting protein 1

 Activating transcription factor 7-interacting protein 1 ELISA Kit
 Activating transcription factor 7-interacting protein 1 Recombinant
 Activating transcription factor 7-interacting protein 1 Antibody
Also known as Activating transcription factor 7-interacting protein 1 (ATFa-associated modulator) (mAM) (MBD1-containing chromatin-associated factor 1).
ATF7IP: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD
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1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells. Belongs to the MCAF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Cellular Component: cytoplasm; nucleoplasm; nucleus; transcription factor complex

Molecular Function: ATPase activity; transcription corepressor activity

Biological Process: DNA methylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcriptional preinitiation complex assembly
 Atf7ip ELISA Kit
 Atf7ip Recombinant
 Atf7ip Antibody
 Mcaf1 ELISA Kit
 Mcaf1 Recombinant
 Mcaf1 Antibody
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Activating transcription factor 7-interacting protein 2

 Activating transcription factor 7-interacting protein 2 ELISA Kit
 Activating transcription factor 7-interacting protein 2 Recombinant
 Activating transcription factor 7-interacting protein 2 Antibody
Also known as Activating transcription factor 7-interacting protein 2 (ATF7-interacting protein 2) (MBD1-containing chromatin-associated factor 2).
ATF7IP2: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-de
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pendent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). Belongs to the MCAF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: cytoplasm; nucleolus; nucleus
 ATF7IP2 ELISA Kit
 ATF7IP2 Recombinant
 ATF7IP2 Antibody
 MCAF2 ELISA Kit
 MCAF2 Recombinant
 MCAF2 Antibody
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