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Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane .

Below are the list of possible Adseverin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.


 Adseverin ELISA Kit
 Adseverin Recombinant
 Adseverin Antibody
Also known as Adseverin (Gelsolin-like protein) (Scinderin).
SCIN: Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation an
d differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes. Belongs to the villin/gelsolin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Cellular Component: brush border; protein complex

Biological Process: actin filament capping; actin filament severing; negative regulation of cell proliferation; positive regulation of actin nucleation; positive regulation of apoptosis; positive regulation of megakaryocyte differentiation; sequestering of actin monomers
 Scin ELISA Kit
 Scin Recombinant
 Scin Antibody
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