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Aldo-keto reductase family

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Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

Below are the list of possible Aldo-keto reductase family products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Aldo-keto reductase family 1 member B10

 Aldo-keto reductase family 1 member B10 ELISA Kit
 Aldo-keto reductase family 1 member B10 Recombinant
 Aldo-keto reductase family 1 member B10 Antibody
Also known as Aldo-keto reductase family 1 member B10 (ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase).
AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the d
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igested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.

Protein type: Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.-; EC 1.1.1.21; Lipid Metabolism - linoleic acid; Oxidoreductase

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: cytosol

Molecular Function: aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity

Biological Process: aldehyde metabolic process; digestion; farnesol catabolic process; retinoid metabolic process; steroid metabolic process
 AKR1B10 ELISA Kit
 AKR1B10 Recombinant
 AKR1B10 Antibody
 AKR1B11 ELISA Kit
 AKR1B11 Recombinant
 AKR1B11 Antibody
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Aldo-keto reductase family 1 member B15

 Aldo-keto reductase family 1 member B15 ELISA Kit
 Aldo-keto reductase family 1 member B15 Recombinant
 Aldo-keto reductase family 1 member B15 Antibody
Also known as Aldo-keto reductase family 1 member B15 (Estradiol 17-beta-dehydrogenase AKR1B15).
AKR1B15: Possesses weak oxidoreductase activity. Belongs to the aldo/keto reductase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.1.1.-; EC 1.1.1.21; EC 1.1.1.62; Oxidoreductase

Chromosomal Location of Human Ortholog: 7q33

Cellu
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lar Component: mitochondrial matrix

Molecular Function: estradiol 17-beta-dehydrogenase activity

Biological Process: estrogen biosynthetic process
 AKR1B15 ELISA Kit
 AKR1B15 Recombinant
 AKR1B15 Antibody
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Aldo-keto reductase family 1 member C1

 Aldo-keto reductase family 1 member C1 ELISA Kit
 Aldo-keto reductase family 1 member C1 Recombinant
 Aldo-keto reductase family 1 member C1 Antibody
Also known as Aldo-keto reductase family 1 member C1 (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2) (High-affinity hepatic bile acid-binding protein) (HB.
AKR1C1: Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. Belongs to the aldo/keto reductase family.<
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Protein type: EC 1.1.1.112; EC 1.1.1.149; EC 1.3.1.20; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 10p15-p14

Cellular Component: cytosol

Molecular Function: 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity; aldehyde reductase activity; aldo-keto reductase activity; bile acid binding; carboxylic acid binding; ketosteroid monooxygenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; phenanthrene 9,10-monooxygenase activity; protein binding; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

Biological Process: bile acid and bile salt transport; bile acid metabolic process; cholesterol absorption; cholesterol homeostasis; digestion; epithelial cell differentiation; progesterone metabolic process; protein homooligomerization; response to organophosphorus; retinal metabolic process; retinoid metabolic process
 AKR1C1 ELISA Kit
 AKR1C1 Recombinant
 AKR1C1 Antibody
 DDH ELISA Kit
 DDH Recombinant
 DDH Antibody
 DDH1 ELISA Kit
 DDH1 Recombinant
 DDH1 Antibody
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Aldo-keto reductase family 1 member C1 homolog

 Aldo-keto reductase family 1 member C1 homolog ELISA Kit
 Aldo-keto reductase family 1 member C1 homolog Recombinant
 Aldo-keto reductase family 1 member C1 homolog Antibody
Also known as Aldo-keto reductase family 1 member C1 homolog (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) (Indanol dehydrogenase).
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile
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acid concentration. May play a role in myelin formation. Can oxidize both 20-alpha- and 3-alpha-hydroxysteroids.
 AKR1C1 ELISA Kit
 AKR1C1 Recombinant
 AKR1C1 Antibody
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Aldo-keto reductase family 1 member C13

 Aldo-keto reductase family 1 member C13 ELISA Kit
 Aldo-keto reductase family 1 member C13 Recombinant
 Aldo-keto reductase family 1 member C13 Antibody
AKR1C13: Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.-; Oxidoreductase

Molecular Function: aldo-keto reductase activity

Biological Process: xenobiotic metabolic process
 Akr1c13 ELISA Kit
 Akr1c13 Recombinant
 Akr1c13 Antibody
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Aldo-keto reductase family 1 member C18

 Aldo-keto reductase family 1 member C18 ELISA Kit
 Aldo-keto reductase family 1 member C18 Recombinant
 Aldo-keto reductase family 1 member C18 Antibody
Also known as Aldo-keto reductase family 1 member C18 (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD).
AKR1C3: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconv
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ert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.149; Lipid Metabolism - arachidonic acid; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450

Cellular Component: cytoplasm; cytosol; intracellular; nucleus

Molecular Function: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; 20-alpha-hydroxysteroid dehydrogenase activity; 3(or 17)-alpha-hydroxysteroid dehydrogenase activity; aldehyde reductase activity; aldo-keto reductase activity; delta4-3-oxosteroid 5beta-reductase activity; geranylgeranyl reductase activity; ketoreductase activity; ketosteroid monooxygenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; phenanthrene 9,10-monooxygenase activity; retinal dehydrogenase activity; retinol dehydrogenase activity

Biological Process: farnesol catabolic process; G-protein coupled receptor protein signaling pathway; parturition; positive regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; progesterone catabolic process; progesterone metabolic process; protein import into nucleus, translocation; regulation of retinoic acid receptor signaling pathway; regulation of steroid biosynthetic process; retinal metabolic process
 Akr1c18 ELISA Kit
 Akr1c18 Recombinant
 Akr1c18 Antibody
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Aldo-keto reductase family 1 member C2

 Aldo-keto reductase family 1 member C2 ELISA Kit
 Aldo-keto reductase family 1 member C2 Recombinant
 Aldo-keto reductase family 1 member C2 Antibody
Also known as Aldo-keto reductase family 1 member C2 (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Trans-1,2-dihydrobenzene-1,2-diol dehydrog.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes
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catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
 AKR1C2 ELISA Kit
 AKR1C2 Recombinant
 AKR1C2 Antibody
 DDH2 ELISA Kit
 DDH2 Recombinant
 DDH2 Antibody
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Aldo-keto reductase family 1 member C21

 Aldo-keto reductase family 1 member C21 ELISA Kit
 Aldo-keto reductase family 1 member C21 Recombinant
 Aldo-keto reductase family 1 member C21 Antibody
Also known as Aldo-keto reductase family 1 member C21 (17-alpha-hydroxysteroid dehydrogenase) (17-alpha-HSD) (3(or 17)-alpha-hydroxysteroid dehydrogenase) (3-alpha-hydroxysteroid dehydrogenase).
AKR1C2: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most pot
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ent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. Defects in AKR1C2 are a cause of 46,XY sex reversal type 8 (SRXY8). A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. Belongs to the aldo/keto reductase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.1.1.357; EC 1.3.1.20; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450

Molecular Function: 3(or 17)-alpha-hydroxysteroid dehydrogenase activity; aldehyde reductase activity; bile acid binding; carboxylic acid binding; ketosteroid monooxygenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; phenanthrene 9,10-monooxygenase activity; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

Biological Process: digestion; epithelial cell differentiation; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; progesterone metabolic process; prostaglandin metabolic process; steroid metabolic process
 Akr1c21 ELISA Kit
 Akr1c21 Recombinant
 Akr1c21 Antibody
Table BarTOPTable Bar
 

Aldo-keto reductase family 1 member C23

 Aldo-keto reductase family 1 member C23 ELISA Kit
 Aldo-keto reductase family 1 member C23 Recombinant
 Aldo-keto reductase family 1 member C23 Antibody
NADP-dependent oxidoreductase that has 20-alpha-hydroxysteroid dehydrogenase activity.
 AKR1C23 ELISA Kit
 AKR1C23 Recombinant
 AKR1C23 Antibody
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Aldo-keto reductase family 1 member C23-like protein

 Aldo-keto reductase family 1 member C23-like protein ELISA Kit
 Aldo-keto reductase family 1 member C23-like protein Recombinant
 Aldo-keto reductase family 1 member C23-like protein Antibody
Also known as Aldo-keto reductase family 1 member C23-like protein (Putative prostaglandin F synthase).
NADP-dependent oxidoreductase involved in steroid metabolism. May act on various hydroxysteroids.
 PGFS ELISA Kit
 PGFS Recombinant
 PGFS Antibody
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Aldo-keto reductase family 1 member C3

 Aldo-keto reductase family 1 member C3 ELISA Kit
 Aldo-keto reductase family 1 member C3 Recombinant
 Aldo-keto reductase family 1 member C3 Antibody
Also known as Aldo-keto reductase family 1 member C3 (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (3-alpha-HSD type II, brain) (3-alpha-hydroxysteroid dehydrogenase type 2) (3-alpha-HSD type 2) (Chlordecone reductase homolog.
AKR1C3: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate i
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nactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.149; Lipid Metabolism - arachidonic acid; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 10p15-p14

Cellular Component: cytoplasm; cytosol; intracellular; nucleus

Molecular Function: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; 3(or 17)-alpha-hydroxysteroid dehydrogenase activity; aldehyde reductase activity; aldo-keto reductase activity; delta4-3-oxosteroid 5beta-reductase activity; geranylgeranyl reductase activity; ketoreductase activity; ketosteroid monooxygenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; phenanthrene 9,10-monooxygenase activity; retinal dehydrogenase activity; retinol dehydrogenase activity

Biological Process: cellular response to starvation; cyclooxygenase pathway; farnesol catabolic process; G-protein coupled receptor protein signaling pathway; keratinocyte differentiation; male gonad development; multicellular organismal macromolecule metabolic process; positive regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; progesterone metabolic process; prostaglandin metabolic process; protein import into nucleus, translocation; regulation of retinoic acid receptor signaling pathway; response to nutrient; retinal metabolic process; retinoid metabolic process; steroid metabolic process
 AKR1C3 ELISA Kit
 AKR1C3 Recombinant
 AKR1C3 Antibody
 DDH1 ELISA Kit
 DDH1 Recombinant
 DDH1 Antibody
 HSD17B5 ELISA Kit
 HSD17B5 Recombinant
 HSD17B5 Antibody
 KIAA0119 ELISA Kit
 KIAA0119 Recombinant
 KIAA0119 Antibody
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Aldo-keto reductase family 1 member C3 homolog

 Aldo-keto reductase family 1 member C3 homolog ELISA Kit
 Aldo-keto reductase family 1 member C3 homolog Recombinant
 Aldo-keto reductase family 1 member C3 homolog Antibody
Also known as Aldo-keto reductase family 1 member C3 homolog (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (3-alpha-hydroxysteroid dehydrogenase type 2) (3-alpha-HSD type 2) (Indanol dehydrogenase) (Prostagland.
Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9
>>>
-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
 AKR1C3 ELISA Kit
 AKR1C3 Recombinant
 AKR1C3 Antibody
Table BarTOPTable Bar
 

Aldo-keto reductase family 1 member C4

 Aldo-keto reductase family 1 member C4 ELISA Kit
 Aldo-keto reductase family 1 member C4 Recombinant
 Aldo-keto reductase family 1 member C4 Antibody
Also known as Aldo-keto reductase family 1 member C4 (3-alpha-HSD1) (3-alpha-hydroxysteroid dehydrogenase type I) (Chlordecone reductase) (CDR) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4).
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogena
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se activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
 AKR1C4 ELISA Kit
 AKR1C4 Recombinant
 AKR1C4 Antibody
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Aldo-keto reductase family 4 member C10

 Aldo-keto reductase family 4 member C10 ELISA Kit
 Aldo-keto reductase family 4 member C10 Recombinant
 Aldo-keto reductase family 4 member C10 Antibody
Oxidoreductase that may act on a broad range of substrates such as ketosteroids, aldehydes, ketones and sugars.
 AKR4C10 ELISA Kit
 AKR4C10 Recombinant
 AKR4C10 Antibody
 At2g37790 ELISA Kit
 At2g37790 Recombinant
 At2g37790 Antibody
 T8P21.30 ELISA Kit
 T8P21.30 Recombinant
 T8P21.30 Antibody
Table BarTOPTable Bar
 

Aldo-keto reductase family 4 member C11

 Aldo-keto reductase family 4 member C11 ELISA Kit
 Aldo-keto reductase family 4 member C11 Recombinant
 Aldo-keto reductase family 4 member C11 Antibody
Oxidoreductase that may act on a broad range of substrates such as ketosteroids, aldehydes, ketones and sugars.
 AKR4C11 ELISA Kit
 AKR4C11 Recombinant
 AKR4C11 Antibody
 At3g53880 ELISA Kit
 At3g53880 Recombinant
 At3g53880 Antibody
 F5K20.180 ELISA Kit
 F5K20.180 Recombinant
 F5K20.180 Antibody
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Aldo-keto reductase family 4 member C8

 Aldo-keto reductase family 4 member C8 ELISA Kit
 Aldo-keto reductase family 4 member C8 Recombinant
 Aldo-keto reductase family 4 member C8 Antibody
Encodes an NADPH-dependent aldo-keto reductase that can act on a wide variety of substrates in vitro including aliphatic and aromatic aldehydes and steroids. Transcript levels for this gene are up-regulated in response to cold, salt, and drought stress.
 AKR4C8 ELISA Kit
 AKR4C8 Recombinant
 AKR4C8 Antibody
 At2g37760 ELISA Kit
 At2g37760 Recombinant
 At2g37760 Antibody
 F13M22 ELISA Kit
 F13M22 Recombinant
 F13M22 Antibody
 T8P21.6 ELISA Kit
 T8P21.6 Recombinant
 T8P21.6 Antibody
Table BarTOPTable Bar
 

Aldo-keto reductase family 4 member C9

 Aldo-keto reductase family 4 member C9 ELISA Kit
 Aldo-keto reductase family 4 member C9 Recombinant
 Aldo-keto reductase family 4 member C9 Antibody
Encodes an NADPH-dependent aldo-keto reductase that can act on a wide variety of substrates in vitro including saturated and unsaturated aldehydes, steroids, and sugars. GFP-tagged AKR4C9 localizes to the chloroplast where it may play a role in detoxifying reactive carbonyl compounds that threaten to impair the photosynthetic process. Transcript levels for this gene are up-regulated in response to cold, salt, and drought stress.
 AKR4C9 ELISA Kit
 AKR4C9 Recombinant
 AKR4C9 Antibody
 At2g37770 ELISA Kit
 At2g37770 Recombinant
 At2g37770 Antibody
 F13M22 ELISA Kit
 F13M22 Recombinant
 F13M22 Antibody
 T8P21.32 ELISA Kit
 T8P21.32 Recombinant
 T8P21.32 Antibody
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