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Alkylated DNA repair protein

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Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain .

Below are the list of possible Alkylated DNA repair protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Alkylated DNA repair protein alkB homolog 8

 Alkylated DNA repair protein alkB homolog 8 ELISA Kit
 Alkylated DNA repair protein alkB homolog 8 Recombinant
 Alkylated DNA repair protein alkB homolog 8 Antibody
Also known as Alkylated DNA repair protein alkB homolog 8 (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8).
ALKBH8: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyz
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es the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis. Belongs to the alkB family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.1.1.229; Methyltransferase; RNA processing

Cellular Component: cytoplasm; cytosol; microtubule cytoskeleton; nucleoplasm; nucleus

Molecular Function: ferrous iron binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; tRNA (uracil) methyltransferase activity; tRNA binding; zinc ion binding

Biological Process: response to DNA damage stimulus; tRNA methylation; tRNA wobble uridine modification
 Alkbh8 ELISA Kit
 Alkbh8 Recombinant
 Alkbh8 Antibody
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