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Alpha-1-macroglobulin

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Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity).

Below are the list of possible Alpha-1-macroglobulin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Alpha-1-macroglobulin

 Alpha-1-macroglobulin ELISA Kit
 Alpha-1-macroglobulin Recombinant
 Alpha-1-macroglobulin Antibody
Also known as Alpha-1-macroglobulin (Alpha-1-M) (Alpha-1-macroglobulin 165 kDa subunit).
plasma protease inhibitor [RGD, Feb 2006]
 A1m ELISA Kit
 A1m Recombinant
 A1m Antibody
 Pzp ELISA Kit
 Pzp Recombinant
 Pzp Antibody
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