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Alpha-ketoglutarate-dependent dioxygenase

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Putative dioxygenase that may repair alkylated DNA or RNA by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).

Below are the list of possible Alpha-ketoglutarate-dependent dioxygenase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Alpha-ketoglutarate-dependent dioxygenase abh1

 Alpha-ketoglutarate-dependent dioxygenase abh1 ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase abh1 Recombinant
 Alpha-ketoglutarate-dependent dioxygenase abh1 Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase abh1 (Alkylated DNA repair protein alkB homolog).
Putative dioxygenase that may repair alkylated DNA or RNA by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron ().
 abh1 ELISA Kit
 abh1 Recombinant
 abh1 Antibody
 SPBC13G1.04c ELISA Kit
 SPBC13G1.04c Recombinant
 SPBC13G1.04c Antibody
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Alpha-ketoglutarate-dependent dioxygenase alkB

 Alpha-ketoglutarate-dependent dioxygenase alkB ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase alkB Recombinant
 Alpha-ketoglutarate-dependent dioxygenase alkB Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase alkB (Alkylated DNA repair protein alkB homolog).
Putative dioxygenase that may repair alkylated DNA or RNA by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron ().
 At1g11780 ELISA Kit
 At1g11780 Recombinant
 At1g11780 Antibody
 F25C20.6 ELISA Kit
 F25C20.6 Recombinant
 F25C20.6 Antibody
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Alpha-ketoglutarate-dependent dioxygenase AlkB homolog

 Alpha-ketoglutarate-dependent dioxygenase AlkB homolog ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase AlkB homolog Recombinant
 Alpha-ketoglutarate-dependent dioxygenase AlkB homolog Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase AlkB homolog (DNA oxidative demethylase AlkB).
Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-me
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thylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) ().
 alkB ELISA Kit
 alkB Recombinant
 alkB Antibody
 CC_0009 ELISA Kit
 CC_0009 Recombinant
 CC_0009 Antibody
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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Recombinant
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Alkylated DNA repair protein alkB homolog 3).
Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m
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3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons. Requires molecular oxygen, alpha-ketoglutarate and iron.
 ALKBH3 ELISA Kit
 ALKBH3 Recombinant
 ALKBH3 Antibody
 ABH3 ELISA Kit
 ABH3 Recombinant
 ABH3 Antibody
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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 Recombinant
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4).
ALKBH4: Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron. Belongs to the alkB family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.11.-

Chromosomal Location of Human Ortholog: 7q22.1 >>>
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Cellular Component: midbody

Molecular Function: actin binding; demethylase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; protein binding

Biological Process: actomyosin structure organization and biogenesis; protein amino acid demethylation
 ALKBH4 ELISA Kit
 ALKBH4 Recombinant
 ALKBH4 Antibody
 ABH4 ELISA Kit
 ABH4 Recombinant
 ABH4 Antibody
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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6

 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 Recombinant
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (Alkylated DNA repair protein alkB homolog 6).
Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron.
 alkbh6 ELISA Kit
 alkbh6 Recombinant
 alkbh6 Antibody
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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7

 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 Recombinant
 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 Antibody
Also known as Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (Alkylated DNA repair protein alkB homolog 7).
May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate. Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. A
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cts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity (). Involved in fatty acid metabolism ().
 ALKBH7 ELISA Kit
 ALKBH7 Recombinant
 ALKBH7 Antibody
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Alpha-ketoglutarate-dependent dioxygenase FTO

 Alpha-ketoglutarate-dependent dioxygenase FTO ELISA Kit
 Alpha-ketoglutarate-dependent dioxygenase FTO Recombinant
 Alpha-ketoglutarate-dependent dioxygenase FTO Antibody
Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent interna
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l modification of messenger RNA (mRNA) in higher eukaryotes. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. May contribute to the regulation of the global metabolic rate, energy expenditure and energy homeostasis ().
 fto ELISA Kit
 fto Recombinant
 fto Antibody
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