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Alpha-like toxin

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This alpha-like toxin binds voltage-dependently sodium channels and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals and insects. Is active on Nav1.4/SCN4A and Nav1.5/SCN5A. Acts as a cardiotoxin. Is 6-fold more toxic than BmK-M2.

Below are the list of possible Alpha-like toxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Alpha-like toxin BmK-M1

 Alpha-like toxin BmK-M1 ELISA Kit
 Alpha-like toxin BmK-M1 Recombinant
 Alpha-like toxin BmK-M1 Antibody
Also known as Alpha-like toxin BmK-M1 (BmK I) (BmK-I) (BmKI) (BmK1) (Bmk M1) (BmKM1).
This alpha-like toxin binds voltage-dependently sodium channels and inhibits the inactivation of the activated
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channels, thereby blocking neuronal transmission. This toxin is active against mammals and insects. Is active on Nav1.4/SCN4A and Nav1.5/SCN5A. Acts as a cardiotoxin. Is 6-fold more toxic than BmK-M2.
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Alpha-like toxin BmK-M2

 Alpha-like toxin BmK-M2 ELISA Kit
 Alpha-like toxin BmK-M2 Recombinant
 Alpha-like toxin BmK-M2 Antibody
Also known as Alpha-like toxin BmK-M2 (BmK M2) (BmKM2).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is
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active against mammals and insects.
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Alpha-like toxin BmK-M4

 Alpha-like toxin BmK-M4 ELISA Kit
 Alpha-like toxin BmK-M4 Recombinant
 Alpha-like toxin BmK-M4 Antibody
Also known as Alpha-like toxin BmK-M4 (BmK4) (BmKM4) (Bmk M4) (BmK-IV).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmissio
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n. This toxin is active against mammals.
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Alpha-like toxin BmK-M7

 Alpha-like toxin BmK-M7 ELISA Kit
 Alpha-like toxin BmK-M7 Recombinant
 Alpha-like toxin BmK-M7 Antibody
Also known as Alpha-like toxin BmK-M7 (BmKM7) (Bmk M7).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. Is active on
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both mammals and insects. Can be considered as a cardiotoxin, as it can bind to human cardiac sodium channel and modify its normal properties.
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Alpha-like toxin Bom3

 Alpha-like toxin Bom3 ELISA Kit
 Alpha-like toxin Bom3 Recombinant
 Alpha-like toxin Bom3 Antibody
Also known as Alpha-like toxin Bom3 (Bom III) (BomIII).
Binds voltage-independently sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmis
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sion. As it competes neither with the classical alpha-toxin AaH2 nor the beta-toxin Css2, this toxin is an alpha-like toxin.
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Alpha-like toxin Bom4

 Alpha-like toxin Bom4 ELISA Kit
 Alpha-like toxin Bom4 Recombinant
 Alpha-like toxin Bom4 Antibody
Also known as Alpha-like toxin Bom4 (Bom IV) (BomIV).
Binds voltage-independently sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmissi
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on. This alpha-like toxin is highly toxic to mice and insects.
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Alpha-like toxin CsEv5

 Alpha-like toxin CsEv5 ELISA Kit
 Alpha-like toxin CsEv5 Recombinant
 Alpha-like toxin CsEv5 Antibody
Also known as Alpha-like toxin CsEv5 (CsE v5) (CsE-v5).
Binds voltage-independently sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmis
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sion. Is highly toxic to insects and barely toxic to mammals. As it does not compete with the classical alpha-toxin AaH2, this toxin is considered as an alpha-like toxin.
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Alpha-like toxin Lqh3

 Alpha-like toxin Lqh3 ELISA Kit
 Alpha-like toxin Lqh3 Recombinant
 Alpha-like toxin Lqh3 Antibody
Also known as Alpha-like toxin Lqh3 (Lqh III) (LqhIII).
Binds voltage-independently at site-3 of sodium channels and inhibits the inactivation of the activated channels, thereby blocking neuronal t
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ransmission. The dissociation is voltage-dependent. This alpha-like toxin is highly toxic to insects and competes with LqhaIT on binding to insect sodium channels. Differs from classical anti-mammalian alpha-toxins as it inhibits sodium channel inactivation in cell bodies of hippocampus brain neurons, on which the anti-mammalian Lqh2 is inactive, and is unable to affect Nav1.2 in the rat brain, on which Lqh2 is highly active. Moreover, its pharmacological properties are unique in that its binding affinity for insect channels drops >30-fold at pH 8.5 versus pH 6.5, and its rate of association with receptor site-3 on both insect and mammalian sodium channels is 4-15-fold slower compared with LqhaIT and Lqh2.
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Alpha-like toxin Lqh6

 Alpha-like toxin Lqh6 ELISA Kit
 Alpha-like toxin Lqh6 Recombinant
 Alpha-like toxin Lqh6 Antibody
Also known as Alpha-like toxin Lqh6 (Lqh VI) (LqhVI).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is h
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ighly toxic to insects and mice, and inhibits the binding of alpha-toxin to cockroach neuronal membranes.
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Alpha-like toxin Lqh7

 Alpha-like toxin Lqh7 ELISA Kit
 Alpha-like toxin Lqh7 Recombinant
 Alpha-like toxin Lqh7 Antibody
Also known as Alpha-like toxin Lqh7 (Lqh VII) (LqhVII).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is
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highly toxic to insects and mice, and inhibits the binding of alpha-toxin to cockroach neuronal membranes.
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Proteins Root Name Listing
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