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Aminoacyl tRNA synthase complex-interacting multifunctional protein

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Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion (By similarity).

Below are the list of possible Aminoacyl tRNA synthase complex-interacting multifunctional protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 ELISA Kit
 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Recombinant
 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Antibody
Also known as Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43).
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding t
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o SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion ().
 AIMP1 ELISA Kit
 AIMP1 Recombinant
 AIMP1 Antibody
 SCYE1 ELISA Kit
 SCYE1 Recombinant
 SCYE1 Antibody
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Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 ELISA Kit
 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Recombinant
 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Antibody
Also known as Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1).
JTV1: Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: cytosol
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; membrane

Molecular Function: protein binding

Biological Process: tRNA aminoacylation for protein translation
 AIMP2 ELISA Kit
 AIMP2 Recombinant
 AIMP2 Antibody
 JTV1 ELISA Kit
 JTV1 Recombinant
 JTV1 Antibody
 PRO0992 ELISA Kit
 PRO0992 Recombinant
 PRO0992 Antibody
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