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Angiomotin

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Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions (By similarity).

Below are the list of possible Angiomotin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Angiomotin

 Angiomotin ELISA Kit
 Angiomotin Recombinant
 Angiomotin Antibody
AMOT: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. Belongs to the angiomotin family. 2 isoforms of the human protein are produced by altern
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ative splicing.

Cellular Component: actin filament; cytoplasmic vesicle; endocytic vesicle; external side of plasma membrane; lamellipodium; ruffle; signalosome; tight junction

Molecular Function: angiostatin binding; protein binding; receptor activity

Biological Process: actin cytoskeleton organization and biogenesis; blood vessel endothelial cell migration; blood vessel morphogenesis; cell migration involved in gastrulation; chemotaxis; gastrulation with mouth forming second; in utero embryonic development; negative regulation of angiogenesis; positive regulation of embryonic development; regulation of cell migration; regulation of small GTPase mediated signal transduction; vasculogenesis
 Amot ELISA Kit
 Amot Recombinant
 Amot Antibody
 Kiaa1071 ELISA Kit
 Kiaa1071 Recombinant
 Kiaa1071 Antibody
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Angiomotin-like 2a

 Angiomotin-like 2a ELISA Kit
 Angiomotin-like 2a Recombinant
 Angiomotin-like 2a Antibody
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments and for cell movements during embryogenesis. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the p
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olarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
 amotl2a ELISA Kit
 amotl2a Recombinant
 amotl2a Antibody
 amotl2 ELISA Kit
 amotl2 Recombinant
 amotl2 Antibody
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