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Anticancerous peptide

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The synthetic peptide inhibits cell proliferation and induces apoptosis in cancer-derived cell lines Hep2 (IC(50)=1.5 mM) and HCT15 and, to a lesser extent, in non-cancerous NIH/3T3 cells. The mode of action is presumably an arrest in the G0/G1 phase. Has DNA-binding activity. Antiproliferative, proapoptotic and DNA-binding activities are increased by acetylation at Ala-1 and Lys-3. Has no hemolytic activity against mouse erythrocytes. Has antibacterial activity against S.epidermitis (MIC=60 ug), B.subtilis (MIC=30 ug), P.aeruginosa (MIC=30 ug) and E.coli strain ATCC 8739 (MIC=30 ug). Antibacterial activity is decreased by acetylation.

Below are the list of possible Anticancerous peptide products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Anticancerous peptide 1

 Anticancerous peptide 1 ELISA Kit
 Anticancerous peptide 1 Recombinant
 Anticancerous peptide 1 Antibody
Also known as Anticancerous peptide 1 (Cr-ACP1).
The synthetic peptide inhibits cell proliferation and induces apoptosis in cancer-derived cell lines Hep2 (IC50=1.5 mM) and HCT15 and, to a lesser e
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xtent, in non-cancerous NIH/3T3 cells. The mode of action is presumably an arrest in the G0/G1 phase. Has DNA-binding activity. Antiproliferative, proapoptotic and DNA-binding activities are increased by acetylation at Ala-1 and Lys-3. Has no hemolytic activity against mouse erythrocytes. Has antibacterial activity against S.epidermitis (MIC=60 µg), B.subtilis (MIC=30 µg), P.aeruginosa (MIC=30 µg) and E.coli strain ATCC 8739 (MIC=30 µg). Antibacterial activity is decreased by acetylation.
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