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AP-1 complex-associated regulatory protein

Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus-end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo-lysosome secretion. Inhibits Arp2/3 complex function; negatively regulates cell spreading, size and motility via intracellular sequestration of the Arp2/3 complex.

Below are the list of possible AP-1 complex-associated regulatory protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

AP-1 complex-associated regulatory protein

 AP-1 complex-associated regulatory protein ELISA Kit
 AP-1 complex-associated regulatory protein Recombinant
 AP-1 complex-associated regulatory protein Antibody
Also known as AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin).
AP1AR: Necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1- adaptin attenuates the release of the AP-1 complex from membranes. 2 isoforms of the human protein are
produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: endosome; Golgi apparatus; transport vesicle

Molecular Function: kinesin binding

Biological Process: negative regulation of receptor recycling; vesicle targeting, trans-Golgi to endosome
 AP1AR Recombinant
 AP1AR Antibody
 C4orf16 ELISA Kit
 C4orf16 Recombinant
 C4orf16 Antibody
 PRO0971 ELISA Kit
 PRO0971 Recombinant
 PRO0971 Antibody
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