Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Apoptotic protease-activating factor  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Haptoglobin Protein
 • Low Density Lipoprotein (LDL) ELISA Kit
 • Notch homolog 4 (Drosophila) (NOTCH4) ELISA Kit
 • Intestinal fat digestive enzyme ELISA Kit
 • Allopregnanolone (AP) ELISA Kit
 • LYSINE-SPECIFIC HISTONE DEMETHYLASE (KDM1A) Antibody
 • eukaryotic translation initiation factor 4E binding protein ... Antibody
 • Brain Natriuretic Peptide (BNP) ELISA Kit
 • Parvovirus (PV) ELISA Kit
 • soluble Human leucocyte antigen G1 (sHLA-G) ELISA Kit
 • ACTL8 Antibody
 • V type proton ATPase catalytic subunit A (ATP6V1A) ELISA Kit
 • Forkhead box protein N2 (foxn2) Recombinant Protein
 • Natural resistance-associated macrophage protein 1 (SLC11A1) Recombinant Protein
 downarrow more ...
separator

Apoptotic protease-activating factor

separator
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).

Below are the list of possible Apoptotic protease-activating factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Apoptotic protease-activating factor 1

 Apoptotic protease-activating factor 1 ELISA Kit
 Apoptotic protease-activating factor 1 Recombinant
 Apoptotic protease-activating factor 1 Antibody
Also known as Apoptotic protease-activating factor 1 (APAF-1).
APAF: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. Monomer. Oligomerizes upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-
>>>
caspase-9 bind to each other via their respective NH2-terminal CARD domains and consecutively mature caspase-9 is released from the complex. Pro-caspase-3 is recruited into the Apaf-1-pro-caspase-9 complex via interaction with pro-caspase-9. Interacts with APIP. Interacts (via CARD and NACHT domains) with NAIP/BIRC1 (via NACHT domain). By E2F and p53/TP53 in apoptotic neurons. Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Cellular Component: apoptosome; cytosol; nucleus

Molecular Function: caspase activator activity; heat shock protein binding; identical protein binding

Biological Process: brain development; caspase activation; caspase activation via cytochrome c; forebrain development; multicellular organismal development; neural tube closure; neuron apoptosis; protein homooligomerization
 Apaf1 ELISA Kit
 Apaf1 Recombinant
 Apaf1 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions