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Astrocytic phosphoprotein

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Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm.

Below are the list of possible Astrocytic phosphoprotein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Astrocytic phosphoprotein PEA-15

 Astrocytic phosphoprotein PEA-15 ELISA Kit
 Astrocytic phosphoprotein PEA-15 Recombinant
 Astrocytic phosphoprotein PEA-15 Antibody
Also known as Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes).
PEA-15: an ubiquitously expressed anti-apoptotic protein. Inhibits both Fas- and Tnfrsf1a/Tnfr1-mediated caspase-8 activity and apoptosis. Interacts with CASP8/FLICE and FADD. Regulates glucose transport by controlling both the content of GLUT1 glucose transporters on the plasma membrane and the insu
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lin-dependent trafficking of GLUT4 from the cell interior to the surface. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.

Protein type: Apoptosis; Motility/polarity/chemotaxis
 PEA15 ELISA Kit
 PEA15 Recombinant
 PEA15 Antibody
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