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Atrial natriuretic peptide receptor

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Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.

Below are the list of possible Atrial natriuretic peptide receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Atrial natriuretic peptide receptor 1

 Atrial natriuretic peptide receptor 1 ELISA Kit
 Atrial natriuretic peptide receptor 1 Recombinant
 Atrial natriuretic peptide receptor 1 Antibody
Also known as Atrial natriuretic peptide receptor 1 (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A).
ANPA: natriuretic peptide receptor A, which mediates natriuretic, diuretic, and vasorelaxing actions of the natriuretic peptides. Contains five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and in
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tracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Has guanylate cyclase activity on binding of ANF. Hypertensive SHR Rat has polymorphism at the locus. Human non-coding polymorphisms can alter expression up to two-fold, and have been associated with hypertension. A coding SNP is associated with hypertension and myocardial infarction.

Protein type: EC 4.6.1.2; Guanylyl cyclase; Kinase, protein; Lyase; Membrane protein, integral; Nucleotide Metabolism - purine; Protein kinase, RGC; Protein kinase, dual-specificity (receptor); RGC family; RGC group; Receptor, misc.

Cellular Component: guanylate cyclase complex, soluble; plasma membrane; receptor complex

Molecular Function: GTP binding; guanylate cyclase activity; hormone binding; natriuretic peptide receptor activity; peptide hormone binding; protein kinase binding

Biological Process: cell surface receptor linked signal transduction; cGMP biosynthetic process; dopamine metabolic process; negative regulation of smooth muscle cell proliferation; positive regulation of cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; regulation of blood pressure
 Npr1 ELISA Kit
 Npr1 Recombinant
 Npr1 Antibody
 Npra ELISA Kit
 Npra Recombinant
 Npra Antibody
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Atrial natriuretic peptide receptor 2

 Atrial natriuretic peptide receptor 2 ELISA Kit
 Atrial natriuretic peptide receptor 2 Recombinant
 Atrial natriuretic peptide receptor 2 Antibody
Also known as Atrial natriuretic peptide receptor 2 (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B).
ANPB: natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Contains five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kin
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ase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. Is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. 21 mutations linked to acromesomelic dysplasia (skeletal malformation). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 4.6.1.2; Guanylyl cyclase; Kinase, protein; Lyase; Membrane protein, integral; Nucleotide Metabolism - purine; Protein kinase, RGC; Protein kinase, dual-specificity (receptor); RGC family; RGC group; Receptor, misc.

Chromosomal Location of Human Ortholog: 9p21-p12

Cellular Component: guanylate cyclase complex, soluble; integral to plasma membrane; plasma membrane

Molecular Function: adenylate cyclase activity; guanylate cyclase activity; hormone binding; natriuretic peptide receptor activity; peptide hormone binding

Biological Process: cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; regulation of blood pressure

Disease: Acromesomelic Dysplasia, Maroteaux Type; Epiphyseal Chondrodysplasia, Miura Type; Short Stature With Nonspecific Skeletal Abnormalities
 NPR2 ELISA Kit
 NPR2 Recombinant
 NPR2 Antibody
 ANPRB ELISA Kit
 ANPRB Recombinant
 ANPRB Antibody
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Atrial natriuretic peptide receptor 3

 Atrial natriuretic peptide receptor 3 ELISA Kit
 Atrial natriuretic peptide receptor 3 Recombinant
 Atrial natriuretic peptide receptor 3 Antibody
Also known as Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C).
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple tra
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nscript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
 NPR3 ELISA Kit
 NPR3 Recombinant
 NPR3 Antibody
 ANPRC ELISA Kit
 ANPRC Recombinant
 ANPRC Antibody
 C5orf23 ELISA Kit
 C5orf23 Recombinant
 C5orf23 Antibody
 NPRC ELISA Kit
 NPRC Recombinant
 NPRC Antibody
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