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Aurora kinase

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Part of a chromosomal passenger complex.

Below are the list of possible Aurora kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Aurora kinase

 Aurora kinase ELISA Kit
 Aurora kinase Recombinant
 Aurora kinase Antibody
Part of a chromosomal passenger complex.
 aurK ELISA Kit
 aurK Recombinant
 aurK Antibody
 AurB ELISA Kit
 AurB Recombinant
 AurB Antibody
 Aurora ELISA Kit
 Aurora Recombinant
 Aurora Antibody
 DDB_G0279343 ELISA Kit
 DDB_G0279343 Recombinant
 DDB_G0279343 Antibody
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Aurora kinase A

 Aurora kinase A ELISA Kit
 Aurora kinase A Recombinant
 Aurora kinase A Antibody
Also known as Aurora kinase A (Aurora 2) (Aurora family kinase 1) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threo.
AurA: a member of the AUR family of kinases. A cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines. Regulated by phosphorylation-dependent proteasomal degradation. Localized to mitotic centrosomes and spindle microtubules and is required for centrosome maturation. Loss of Aurora A leads to d
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efective mitotic spindles and gross errors in chromosome segregation. Required for centrosome duplication and chromosome segregation. Overexpression in culture drives transformation and aneuploidy, and negatively regulates p53. Amplified or overexpressed in many tumors or cell lines. Found as a skin tumor susceptibility gene in mouse, and a human SNP in a degradation domain is weakly cancer-associated and undergoes allele-specific amplification. Inhibitors: VX-680, ZM447439, Hesperadin, SNS-595.

Protein type: AUR family; EC 2.7.11.1; Kinase, protein; Oncoprotein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)

Cellular Component: axon hillock; centrosome; condensed nuclear chromosome, pericentric region; germinal vesicle; microtubule cytoskeleton; microtubule organizing center; nucleus; perinuclear region of cytoplasm; pronucleus; spindle; spindle microtubule; spindle midzone; spindle pole centrosome

Molecular Function: histone serine kinase activity; protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; ubiquitin protein ligase binding

Biological Process: anterior/posterior axis specification; centrosome localization; centrosome organization and biogenesis; meiosis; meiotic spindle organization and biogenesis; microtubule cytoskeleton organization and biogenesis; mitosis; mitotic cell cycle; mitotic centrosome separation; mitotic spindle organization and biogenesis; negative regulation of apoptosis; negative regulation of protein binding; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of cytokinesis; regulation of protein stability; response to wounding; spindle assembly involved in female meiosis I; spindle organization and biogenesis
 Aurka ELISA Kit
 Aurka Recombinant
 Aurka Antibody
 Aik ELISA Kit
 Aik Recombinant
 Aik Antibody
 Airk ELISA Kit
 Airk Recombinant
 Airk Antibody
 Ark1 ELISA Kit
 Ark1 Recombinant
 Ark1 Antibody
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Aurora kinase A-A

 Aurora kinase A-A ELISA Kit
 Aurora kinase A-A Recombinant
 Aurora kinase A-A Antibody
Also known as Aurora kinase A-A (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 6-A) (Serine/threonine-protein kinase Eg2-A) (pEg2) (Serine/threonine-protein kinase aurora-A) (p46Eg265).
AurA: a member of the AUR family of kinases. A cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines. Regulated by phosphorylation-dependent proteasomal degradation. Localized to mitotic centrosomes and spindle microtubules and is required for centrosome maturation. Loss of Aurora A leads to defective mitotic spi
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ndles and gross errors in chromosome segregation. Required for centrosome duplication and chromosome segregation. Overexpression in culture drives transformation and aneuploidy, and negatively regulates p53. Amplified or overexpressed in many tumors or cell lines. Found as a skin tumor susceptibility gene in mouse, and a human SNP in a degradation domain is weakly cancer-associated and undergoes allele-specific amplification. Inhibitors: VX-680, ZM447439, Hesperadin, SNS-595.

Protein type: AUR family; EC 2.7.11.1; Kinase, protein; Oncoprotein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
 aurka-a ELISA Kit
 aurka-a Recombinant
 aurka-a Antibody
 aurka ELISA Kit
 aurka Recombinant
 aurka Antibody
 eg2 ELISA Kit
 eg2 Recombinant
 eg2 Antibody
 stk6 ELISA Kit
 stk6 Recombinant
 stk6 Antibody
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Aurora kinase A-B

 Aurora kinase A-B ELISA Kit
 Aurora kinase A-B Recombinant
 Aurora kinase A-B Antibody
Also known as Aurora kinase A-B (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 6-B) (Serine/threonine-protein kinase Eg2-B) (Serine/threonine-protein kinase aurora-A) (p46XlEg22).
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spin
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dle assembly checkpoint, and cytokinesis. Phosphorylates numerous target proteins. Important for microtubule formation and/or stabilization ().
 aurka-b ELISA Kit
 aurka-b Recombinant
 aurka-b Antibody
 aurka ELISA Kit
 aurka Recombinant
 aurka Antibody
 eg2 ELISA Kit
 eg2 Recombinant
 eg2 Antibody
 stk6 ELISA Kit
 stk6 Recombinant
 stk6 Antibody
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Aurora kinase B

 Aurora kinase B ELISA Kit
 Aurora kinase B Recombinant
 Aurora kinase B Antibody
Also known as Aurora kinase B (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine.
AurB: a member of the AUR family of kinases. May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Expressed during S and G2/M phase and expression is upregulated in cancer cells during M phase. Localized to the midzone of central spindle in la
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te anaphase and concentrated into the midbody in telophase and cytokinesis. Colocalizes with gamma tubulin in the mid-body. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Overexpressed in colorectal and other cancer cell lines and thought to cause aneuploidy via histone phosphorylation.

Protein type: AUR family; EC 2.7.11.1; Kinase, protein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)

Cellular Component: condensed nuclear chromosome, pericentric region; midbody; nucleus; spindle microtubule; spindle pole centrosome

Molecular Function: histone serine kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity

Biological Process: abscission; mitotic spindle organization and biogenesis; negative regulation of B cell apoptosis; negative regulation of cytokinesis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cytokinesis; protein amino acid phosphorylation; spindle midzone assembly involved in mitosis
 AURKB ELISA Kit
 AURKB Recombinant
 AURKB Antibody
 AIK2 ELISA Kit
 AIK2 Recombinant
 AIK2 Antibody
 AIM1 ELISA Kit
 AIM1 Recombinant
 AIM1 Antibody
 AIRK2 ELISA Kit
 AIRK2 Recombinant
 AIRK2 Antibody
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Aurora kinase B-A

 Aurora kinase B-A ELISA Kit
 Aurora kinase B-A Recombinant
 Aurora kinase B-A Antibody
Also known as Aurora kinase B-A (Aurora/IPL1-related kinase 2-A) (AIRK2-A) (XAIRK2-A) (Serine/threonine-protein kinase 12-A) (Serine/threonine-protein kinase aurora-B-A) (xAurora-B).
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct
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chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Phosphorylates 'Ser-10' of histone H3 during mitosis.
 aurkb-a ELISA Kit
 aurkb-a Recombinant
 aurkb-a Antibody
 airk2-a ELISA Kit
 airk2-a Recombinant
 airk2-a Antibody
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Aurora kinase B-B

 Aurora kinase B-B ELISA Kit
 Aurora kinase B-B Recombinant
 Aurora kinase B-B Antibody
Also known as Aurora kinase B-B (Aurora/IPL1-related kinase 2-B) (AIRK2-B) (XAIRK2-B) (Serine/threonine-protein kinase 12-B) (Serine/threonine-protein kinase aurora-B-B) (xAurora-B-B).
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring corre
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ct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Phosphorylates 'Ser-10' of histone H3 during mitosis ().
 aurkb-b ELISA Kit
 aurkb-b Recombinant
 aurkb-b Antibody
 airk2-b ELISA Kit
 airk2-b Recombinant
 airk2-b Antibody
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Aurora kinase C

 Aurora kinase C ELISA Kit
 Aurora kinase C Recombinant
 Aurora kinase C Antibody
Also known as Aurora kinase C (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 1) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C).
AurC: a member of the AUR family of kinases. May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. Localized to centrosome from anaphase to cytokinesis. Two splice-variant isoforms have been described.

Protein type: AUR family; EC 2.7.11.1; Kinase, protein; Other group; Protein kinase, Other; Protein kinase, S
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er/Thr (non-receptor)

Cellular Component: chromosome; chromosome, pericentric region; condensed chromosome; condensed nuclear chromosome, pericentric region; midbody; spindle microtubule; spindle midzone; spindle pole centrosome

Molecular Function: histone serine kinase activity; protein kinase activity; protein serine/threonine/tyrosine kinase activity

Biological Process: mitotic spindle organization and biogenesis; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of cytokinesis
 Aurkc ELISA Kit
 Aurkc Recombinant
 Aurkc Antibody
 Aie1 ELISA Kit
 Aie1 Recombinant
 Aie1 Antibody
 Aik3 ELISA Kit
 Aik3 Recombinant
 Aik3 Antibody
 Airk3 ELISA Kit
 Airk3 Recombinant
 Airk3 Antibody
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Proteins Root Name Listing
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