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B-cell antigen receptor complex-associated protein

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Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells (By similarity).

Below are the list of possible B-cell antigen receptor complex-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

B-cell antigen receptor complex-associated protein alpha chain

 B-cell antigen receptor complex-associated protein alpha chain ELISA Kit
 B-cell antigen receptor complex-associated protein alpha chain Recombinant
 B-cell antigen receptor complex-associated protein alpha chain Antibody
Also known as B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (CD antigen CD79a).
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR su
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rface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells ().
 CD79A ELISA Kit
 CD79A Recombinant
 CD79A Antibody
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B-cell antigen receptor complex-associated protein beta chain

 B-cell antigen receptor complex-associated protein beta chain ELISA Kit
 B-cell antigen receptor complex-associated protein beta chain Recombinant
 B-cell antigen receptor complex-associated protein beta chain Antibody
Also known as B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b).
Ig-beta: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late
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endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79B are the cause of agammaglobulinemia type 6 (AGM6). It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: B cell receptor complex; cytoplasm; external side of plasma membrane; Golgi apparatus; integral to plasma membrane; nucleoplasm; plasma membrane

Molecular Function: protein binding

Biological Process: B cell differentiation; B cell receptor signaling pathway
 Cd79b ELISA Kit
 Cd79b Recombinant
 Cd79b Antibody
 Igb ELISA Kit
 Igb Recombinant
 Igb Antibody
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