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B-cell lymphoma 3 protein

Below are the list of possible B-cell lymphoma 3 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

B-cell lymphoma 3 protein

 B-cell lymphoma 3 protein ELISA Kit
 B-cell lymphoma 3 protein Recombinant
 B-cell lymphoma 3 protein Antibody
Also known as B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3).
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls t
he nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]
 BCL3 Recombinant
 BCL3 Antibody
 BCL4 Recombinant
 BCL4 Antibody
 D19S37 ELISA Kit
 D19S37 Recombinant
 D19S37 Antibody
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B-cell lymphoma 3 protein homolog

 B-cell lymphoma 3 protein homolog ELISA Kit
 B-cell lymphoma 3 protein homolog Recombinant
 B-cell lymphoma 3 protein homolog Antibody
Also known as B-cell lymphoma 3 protein homolog (BCL-3).
Bcl-3: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. A
chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(14;19)(q32;q13.1) with immunoglobulin gene regions.

Protein type: Apoptosis; Nuclear receptor co-regulator; Oncoprotein; Transcription regulation

Cellular Component: Bcl3/NF-kappaB2 complex; cytoplasm; intercellular bridge; nucleoplasm; nucleus; protein complex

Molecular Function: DNA binding; protein binding; transcription factor activity; transcription factor binding

Biological Process: antimicrobial humoral response; defense response to bacterium; defense response to protozoan; DNA damage response, signal transduction by p53 class mediator; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; extracellular matrix organization and biogenesis; follicular dendritic cell differentiation; germinal center formation; humoral immune response mediated by circulating immunoglobulin; I-kappaB kinase/NF-kappaB cascade; marginal zone B cell differentiation; negative regulation of apoptosis; negative regulation of interleukin-8 biosynthetic process; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor biosynthetic process; positive regulation of interferon-gamma production; positive regulation of interleukin-10 biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of translation; protein import into nucleus, translocation; regulation of apoptosis; response to DNA damage stimulus; response to UV-C; response to virus; spleen development; T-helper 1 type immune response; T-helper 2 cell differentiation; transcription, DNA-dependent
 Bcl3 ELISA Kit
 Bcl3 Recombinant
 Bcl3 Antibody
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