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B-lymphocyte antigen

Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Below are the list of possible B-lymphocyte antigen products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

B-lymphocyte antigen CD19

 B-lymphocyte antigen CD19 ELISA Kit
 B-lymphocyte antigen CD19 Recombinant
 B-lymphocyte antigen CD19 Antibody
Also known as B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19).
CD19: a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calc
ium levels and decreases the threshold for antigen receptor signaling. Germinal center formation is significantly reduced in CD19-deficient mice.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: external side of plasma membrane; integral to plasma membrane; plasma membrane; protein complex

Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; receptor signaling protein activity

Biological Process: B cell receptor signaling pathway; cell surface receptor linked signal transduction; cellular defense response; phosphoinositide-mediated signaling; regulation of immune response; regulation of phosphoinositide 3-kinase cascade

Disease: Immunodeficiency, Common Variable, 2; Immunodeficiency, Common Variable, 3
 CD19 Recombinant
 CD19 Antibody
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B-lymphocyte antigen CD20

 B-lymphocyte antigen CD20 ELISA Kit
 B-lymphocyte antigen CD20 Recombinant
 B-lymphocyte antigen CD20 Antibody
Also known as B-lymphocyte antigen CD20 (B-cell differentiation antigen Ly-44) (Lymphocyte antigen 44) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20).
MS4A1: This protein may be involved in the regulation of B-cell activation and proliferation. Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defe
ct results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Belongs to the MS4A family.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: external side of plasma membrane; extracellular space

Molecular Function: epidermal growth factor receptor binding
 Ms4a1 ELISA Kit
 Ms4a1 Recombinant
 Ms4a1 Antibody
 Cd20 ELISA Kit
 Cd20 Recombinant
 Cd20 Antibody
 Ly-44 ELISA Kit
 Ly-44 Recombinant
 Ly-44 Antibody
 Ms4a2 ELISA Kit
 Ms4a2 Recombinant
 Ms4a2 Antibody
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