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Baculoviral IAP repeat-containing protein

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Below are the list of possible Baculoviral IAP repeat-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Baculoviral IAP repeat-containing protein 1

 Baculoviral IAP repeat-containing protein 1 ELISA Kit
 Baculoviral IAP repeat-containing protein 1 Recombinant
 Baculoviral IAP repeat-containing protein 1 Antibody
Also known as Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).
BIRC1: Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as
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a mediator of neuronal survival in pathological conditions. Prevents motor- neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.

Chromosomal Location of Human Ortholog: 5q13.2

Cellular Component: basolateral plasma membrane; cytoplasm

Molecular Function: ATP binding; protein binding; ubiquitin-protein ligase activity

Biological Process: negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of neuron apoptosis; nervous system development; regulation of signal transduction
 NAIP ELISA Kit
 NAIP Recombinant
 NAIP Antibody
 BIRC1 ELISA Kit
 BIRC1 Recombinant
 BIRC1 Antibody
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Baculoviral IAP repeat-containing protein 1a

 Baculoviral IAP repeat-containing protein 1a ELISA Kit
 Baculoviral IAP repeat-containing protein 1a Recombinant
 Baculoviral IAP repeat-containing protein 1a Antibody
Also known as Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).
BIRC1: Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor- neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems t
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o be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.

Cellular Component: basolateral plasma membrane; cell soma; cytoplasm; neuron projection; perikaryon

Molecular Function: caspase inhibitor activity; ubiquitin-protein ligase activity

Biological Process: negative regulation of apoptosis; negative regulation of caspase activity; regulation of signal transduction
 Naip1 ELISA Kit
 Naip1 Recombinant
 Naip1 Antibody
 Birc1a ELISA Kit
 Birc1a Recombinant
 Birc1a Antibody
 Naip ELISA Kit
 Naip Recombinant
 Naip Antibody
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Baculoviral IAP repeat-containing protein 1b

 Baculoviral IAP repeat-containing protein 1b ELISA Kit
 Baculoviral IAP repeat-containing protein 1b Recombinant
 Baculoviral IAP repeat-containing protein 1b Antibody
Also known as Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).
NAIP2: Sensor component of the NLRC4 inflammasome that specifically recognizes and binds type III secretion system (T3SS) rod proteins such as S.typhimurium (Salmonella) PrgJ and B.thailandensis BsaK from pathogenic bacteria. Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response
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to a range of intracellular bacteria. The NLRC4 inflammasome senses Gram-negative bacteria such as L.pneumophila and P.aeruginosa, enteric pathogens S.typhimurium (Salmonella) and S.flexneri. Prevents motor-neuron apoptosis induced by a variety of signals.

Protein type: Apoptosis

Molecular Function: ATP binding; ubiquitin-protein ligase activity

Biological Process: defense response to bacterium; detection of bacterium; inflammatory response; negative regulation of caspase activity; regulation of signal transduction
 Naip2 ELISA Kit
 Naip2 Recombinant
 Naip2 Antibody
 Birc1b ELISA Kit
 Birc1b Recombinant
 Birc1b Antibody
 Naip-rs6 ELISA Kit
 Naip-rs6 Recombinant
 Naip-rs6 Antibody
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Baculoviral IAP repeat-containing protein 1e

 Baculoviral IAP repeat-containing protein 1e ELISA Kit
 Baculoviral IAP repeat-containing protein 1e Recombinant
 Baculoviral IAP repeat-containing protein 1e Antibody
Also known as Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).
NAIP5: Sensor component of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria such as Legionella or Salmonella. Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. The NLRC4 inflammasome senses
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Gram-negative bacteria such as L.pneumophila and P.aeruginosa, enteric pathogens S.typhimurium (Salmonella) and S.flexneri. Prevents motor-neuron apoptosis induced by a variety of signals.

Cellular Component: cell soma; cytoplasm; neuron projection; perikaryon

Molecular Function: ubiquitin-protein ligase activity

Biological Process: defense response to bacterium; defense response to Gram-negative bacterium; detection of bacterium; inflammatory response; regulation of signal transduction
 Naip5 ELISA Kit
 Naip5 Recombinant
 Naip5 Antibody
 Birc1e ELISA Kit
 Birc1e Recombinant
 Birc1e Antibody
 Naip-rs3 ELISA Kit
 Naip-rs3 Recombinant
 Naip-rs3 Antibody
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Baculoviral IAP repeat-containing protein 1f

 Baculoviral IAP repeat-containing protein 1f ELISA Kit
 Baculoviral IAP repeat-containing protein 1f Recombinant
 Baculoviral IAP repeat-containing protein 1f Antibody
Also known as Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).
Naip6:

Cellular Component: cell soma; cytoplasm; neuron projection; perikaryon

Molecular Function: ubiquitin-protein ligase activity

Biological Process: defense response to bacterium; detection of bacterium; inflammatory response; regulation of signal transduction
 Naip6 ELISA Kit
 Naip6 Recombinant
 Naip6 Antibody
 Birc1f ELISA Kit
 Birc1f Recombinant
 Birc1f Antibody
 Naip-rs4 ELISA Kit
 Naip-rs4 Recombinant
 Naip-rs4 Antibody
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Baculoviral IAP repeat-containing protein 1g

 Baculoviral IAP repeat-containing protein 1g ELISA Kit
 Baculoviral IAP repeat-containing protein 1g Recombinant
 Baculoviral IAP repeat-containing protein 1g Antibody
Also known as Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).
Naip7: Prevents motor-neuron apoptosis induced by a variety of signals.

Cellular Component: cytoplasm

Molecular Function: ubiquitin-protein ligase activity

Biological Process: regulation of signal transduction
 Naip7 ELISA Kit
 Naip7 Recombinant
 Naip7 Antibody
 Birc1g ELISA Kit
 Birc1g Recombinant
 Birc1g Antibody
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Baculoviral IAP repeat-containing protein 2

 Baculoviral IAP repeat-containing protein 2 ELISA Kit
 Baculoviral IAP repeat-containing protein 2 Recombinant
 Baculoviral IAP repeat-containing protein 2 Antibody
Also known as Baculoviral IAP repeat-containing protein 2 (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-sign.
cIAP1: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-c
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anonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin- protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, TRAF2, DIABLO/SMAC, MAP3K14/NIK, MAP3K5/ASK1, IKBKG/NEMO and MXD1/MAD1. Can also function as an E3 ubiquitin- protein ligase of the NEDD8 conjugation pathway, targeting effector caspases for neddylation and inactivation. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8. Can stimulate the transcriptional activity of E2F1. Plays a role in the modulation of the cell cycle. Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. Interacts with CASP9. Interacts (via BIR domains) with TRAF2. Interacts with E2F1, RIPK1, RIPK2, RIPK3, RIPK4, BIRC5/survivin and USP19. Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes. The CARD domain inhibits the activation of E3 ubiquitin ligase activity by preventing RING domain dimerization and E2 ubiquitin donor binding and activation. The CARD domain- mediated autoinhibition of the E3 ubiquitin-protein ligase activity suppresses cell proliferation and migration. USP19 regulates the stability of BIRC2/c-IAP1 by preventing its ubiquitination. Belongs to the IAP family.

Protein type: EC 6.3.2.-; Ligase; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 11q22

Cellular Component: cytoplasm; cytosol; internal side of plasma membrane; nucleus; spindle microtubule

Molecular Function: caspase inhibitor activity; chaperone binding; protein binding; protein N-terminus binding; transcription coactivator activity; transferase activity; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding

Biological Process: cell structure disassembly during apoptosis; cell surface receptor linked signal transduction; I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of apoptosis; regulation of cell cycle; regulation of cell differentiation; regulation of cell proliferation; regulation of inflammatory response; regulation of innate immune response; regulation of toll-like receptor signaling pathway; tumor necrosis factor-mediated signaling pathway
 BIRC2 ELISA Kit
 BIRC2 Recombinant
 BIRC2 Antibody
 API1 ELISA Kit
 API1 Recombinant
 API1 Antibody
 MIHB ELISA Kit
 MIHB Recombinant
 MIHB Antibody
 RNF48 ELISA Kit
 RNF48 Recombinant
 RNF48 Antibody
Table BarTOPTable Bar
 

Baculoviral IAP repeat-containing protein 3

 Baculoviral IAP repeat-containing protein 3 ELISA Kit
 Baculoviral IAP repeat-containing protein 3 Recombinant
 Baculoviral IAP repeat-containing protein 3 Antibody
Also known as Baculoviral IAP repeat-containing protein 3 (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin tran.
cIAP2: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-ca
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nonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin- protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase- independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8. Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Interacts with RIP1, RIP2, RIP3, RIP4 and USP19. Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. USP19 regulates the stability of BIRC3/c-IAP2 by preventing its ubiquitination. Belongs to the IAP family.

Protein type: Apoptosis; EC 6.3.2.-; Ligase; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 11q22

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; spindle microtubule

Molecular Function: caspase inhibitor activity; protein binding; transferase activity; ubiquitin-protein ligase activity

Biological Process: cell surface receptor linked signal transduction; I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein ubiquitination; regulation of apoptosis; regulation of inflammatory response; regulation of innate immune response; regulation of toll-like receptor signaling pathway; tumor necrosis factor-mediated signaling pathway
 BIRC3 ELISA Kit
 BIRC3 Recombinant
 BIRC3 Antibody
 API2 ELISA Kit
 API2 Recombinant
 API2 Antibody
 MIHC ELISA Kit
 MIHC Recombinant
 MIHC Antibody
 RNF49 ELISA Kit
 RNF49 Recombinant
 RNF49 Antibody
Table BarTOPTable Bar
 

Baculoviral IAP repeat-containing protein 5

 Baculoviral IAP repeat-containing protein 5 ELISA Kit
 Baculoviral IAP repeat-containing protein 5 Recombinant
 Baculoviral IAP repeat-containing protein 5 Antibody
Also known as Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin).
Survivin: an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: chromosome, pericentric region; cytoplasm; cy
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tosol; midbody; nuclear chromosome; nucleoplasm; nucleus

Molecular Function: chaperone binding; enzyme binding; identical protein binding; microtubule binding; protein binding; Ran GTPase binding; ubiquitin-protein ligase activity

Biological Process: negative regulation of apoptosis; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; protein amino acid phosphorylation; protein complex localization; protein sumoylation; regulation of apoptosis; regulation of signal transduction; sister chromatid cohesion
 BIRC5 ELISA Kit
 BIRC5 Recombinant
 BIRC5 Antibody
 API4 ELISA Kit
 API4 Recombinant
 API4 Antibody
 IAP4 ELISA Kit
 IAP4 Recombinant
 IAP4 Antibody
Table BarTOPTable Bar
 

Baculoviral IAP repeat-containing protein 5.1

 Baculoviral IAP repeat-containing protein 5.1 ELISA Kit
 Baculoviral IAP repeat-containing protein 5.1 Recombinant
 Baculoviral IAP repeat-containing protein 5.1 Antibody
Also known as Baculoviral IAP repeat-containing protein 5.1 (Survivin1).
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Stimulates the mit
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otic kinase activity of aurkb/aurora-B in the CPC. Does not appear to exhibit anti-apoptotic activity ().
 birc5.1 ELISA Kit
 birc5.1 Recombinant
 birc5.1 Antibody
 TEgg052f17.1 ELISA Kit
 TEgg052f17.1 Recombinant
 TEgg052f17.1 Antibody
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Baculoviral IAP repeat-containing protein 5.1-A

 Baculoviral IAP repeat-containing protein 5.1-A ELISA Kit
 Baculoviral IAP repeat-containing protein 5.1-A Recombinant
 Baculoviral IAP repeat-containing protein 5.1-A Antibody
Also known as Baculoviral IAP repeat-containing protein 5.1-A (Bir1-A protein) (Survivin/XBIR1) (XBIR1) (Survivin1-a) (XSurvivin1) (XSurvivin1A) (Xsvv1) (xSurvivin).
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Stimulates the mitotic kinase activity of aurkb/aurora-B in the CPC. Does not appear to exhibit anti-apoptotic activity.
 birc5.1-a ELISA Kit
 birc5.1-a Recombinant
 birc5.1-a Antibody
 bir1-A ELISA Kit
 bir1-A Recombinant
 bir1-A Antibody
 svv1 ELISA Kit
 svv1 Recombinant
 svv1 Antibody
Table BarTOPTable Bar
 

Baculoviral IAP repeat-containing protein 5.1-B

 Baculoviral IAP repeat-containing protein 5.1-B ELISA Kit
 Baculoviral IAP repeat-containing protein 5.1-B Recombinant
 Baculoviral IAP repeat-containing protein 5.1-B Antibody
Also known as Baculoviral IAP repeat-containing protein 5.1-B (Survivin1-B) (Survivin) (XSurvivin1B) (xL_Survivin2) (Su2).
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stab
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ilization and spindle assembly. Stimulates the mitotic kinase activity of aurkb/aurora-B in the CPC. Does not appear to exhibit anti-apoptotic activity (). CPC. Does not appear to exhibit anti-apoptotic activity.
 birc5.1-b ELISA Kit
 birc5.1-b Recombinant
 birc5.1-b Antibody
 su2 ELISA Kit
 su2 Recombinant
 su2 Antibody
Table BarTOPTable Bar
 

Baculoviral IAP repeat-containing protein 5.2

 Baculoviral IAP repeat-containing protein 5.2 ELISA Kit
 Baculoviral IAP repeat-containing protein 5.2 Recombinant
 Baculoviral IAP repeat-containing protein 5.2 Antibody
Also known as Baculoviral IAP repeat-containing protein 5.2 (Survivin 2) (Survivin).
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Does not appear to exhibit anti-apoptotic activity. Plays a role in increasing blood vessel size during development ().
 birc5.2 ELISA Kit
 birc5.2 Recombinant
 birc5.2 Antibody
 TGas042b13.1 ELISA Kit
 TGas042b13.1 Recombinant
 TGas042b13.1 Antibody
 TGas101d21.1 ELISA Kit
 TGas101d21.1 Recombinant
 TGas101d21.1 Antibody
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Baculoviral IAP repeat-containing protein 5.2-A

 Baculoviral IAP repeat-containing protein 5.2-A ELISA Kit
 Baculoviral IAP repeat-containing protein 5.2-A Recombinant
 Baculoviral IAP repeat-containing protein 5.2-A Antibody
Also known as Baculoviral IAP repeat-containing protein 5.2-A (Survivin2-A) (xSurvivin2A) (xSvv2/SIX) (xL_Survivin1) (Su1).
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (). Does not appear to exhibit anti-apoptotic activity. Plays a role in increasing blood vessel size during development.
 birc5.2-a ELISA Kit
 birc5.2-a Recombinant
 birc5.2-a Antibody
 su1 ELISA Kit
 su1 Recombinant
 su1 Antibody
 svv2 ELISA Kit
 svv2 Recombinant
 svv2 Antibody
Table BarTOPTable Bar
 

Baculoviral IAP repeat-containing protein 5.2-B

 Baculoviral IAP repeat-containing protein 5.2-B ELISA Kit
 Baculoviral IAP repeat-containing protein 5.2-B Recombinant
 Baculoviral IAP repeat-containing protein 5.2-B Antibody
Also known as Baculoviral IAP repeat-containing protein 5.2-B (Survivin in Xenopus) (SIX) (Survivin2-B) (XSurvivin2B).
Does not appear to exhibit anti-apoptotic activity. Plays a role in increasing blood vessel size during development (). Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centro
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mere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.
 birc5.2-b ELISA Kit
 birc5.2-b Recombinant
 birc5.2-b Antibody
 six ELISA Kit
 six Recombinant
 six Antibody
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Baculoviral IAP repeat-containing protein 6

 Baculoviral IAP repeat-containing protein 6 ELISA Kit
 Baculoviral IAP repeat-containing protein 6 Recombinant
 Baculoviral IAP repeat-containing protein 6 Antibody
Also known as Baculoviral IAP repeat-containing protein 6 (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON).
BIRC6: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation syst
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em in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. Homodimer. Binds the activated, processed forms of CASP3, CASP6, CASP7 and CASP9. Interacts with RNF41, DIABLO/SMAC, HTRA2, KIF23/MKLP1, USP8/UBPY, BIRC5/survivin, MAP2K1/MEK1, RAB8A/RAB8, RAB11A/RAB11, PLK1, EXOC3/SEC6 and EXOC4/SEC8. Expressed in brain cancer cells. Inhibited by DIABLO/SMAC, HTRA2, CASP3, CASP6, CASP7 and CASP9.

Protein type: EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 2p22.3

Cellular Component: endosome; membrane; microtubule organizing center; midbody; spindle pole; trans-Golgi network

Molecular Function: cysteine protease inhibitor activity; protein binding; ubiquitin-protein ligase activity

Biological Process: negative regulation of apoptosis; protein amino acid phosphorylation; protein ubiquitination; regulation of cell proliferation; regulation of cytokinesis
 BIRC6 ELISA Kit
 BIRC6 Recombinant
 BIRC6 Antibody
 KIAA1289 ELISA Kit
 KIAA1289 Recombinant
 KIAA1289 Antibody
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Baculoviral IAP repeat-containing protein 7

 Baculoviral IAP repeat-containing protein 7 ELISA Kit
 Baculoviral IAP repeat-containing protein 7 Recombinant
 Baculoviral IAP repeat-containing protein 7 Antibody
Also known as Baculoviral IAP repeat-containing protein 7 (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX) (RING-type E3 ubiquitin transferase BIRC7).
Weak apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Weak inhibitor of caspase activity.
 birc7 ELISA Kit
 birc7 Recombinant
 birc7 Antibody
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Baculoviral IAP repeat-containing protein 7-A

 Baculoviral IAP repeat-containing protein 7-A ELISA Kit
 Baculoviral IAP repeat-containing protein 7-A Recombinant
 Baculoviral IAP repeat-containing protein 7-A Antibody
Also known as Baculoviral IAP repeat-containing protein 7-A (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (RING-type E3 ubiquitin transferase EIAP-A) (XIAP homolog XLX) (XLX).
Weak apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Weak inhibitor of caspase activity.
 birc7-a ELISA Kit
 birc7-a Recombinant
 birc7-a Antibody
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Baculoviral IAP repeat-containing protein 7-B

 Baculoviral IAP repeat-containing protein 7-B ELISA Kit
 Baculoviral IAP repeat-containing protein 7-B Recombinant
 Baculoviral IAP repeat-containing protein 7-B Antibody
Also known as Baculoviral IAP repeat-containing protein 7-B (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B) (RING-type E3 ubiquitin transferase EIAP-B).
Weak apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Weak inhibitor of caspase activity.
 birc7-b ELISA Kit
 birc7-b Recombinant
 birc7-b Antibody
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Baculoviral IAP repeat-containing protein 8

 Baculoviral IAP repeat-containing protein 8 ELISA Kit
 Baculoviral IAP repeat-containing protein 8 Recombinant
 Baculoviral IAP repeat-containing protein 8 Antibody
Also known as Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2).
Protects against apoptosis mediated by BAX.
 BIRC8 ELISA Kit
 BIRC8 Recombinant
 BIRC8 Antibody
 ILP2 ELISA Kit
 ILP2 Recombinant
 ILP2 Antibody
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