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Bengalin

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Toxin that shows cardiotoxicity on isolated guinea pig heart and auricle and neurotoxicity on isolated rat phrenic nerve diaphragm. Shows antiosteoporosis activity in experimental rats. Also induces apoptosis against human leukemic cells (U937 and K562). Has no effect on normal human lymphocytes. Apoptosis has been evidenced from damaged nuclei, cell cycle arrest at sub G1 phase, increase of early apoptotic cells, augmentation of DNA fragmentation and also a reduction of telomerase activity. Also elicits loss of mitochondrial membrane potential (MMP) which induces cytochrome c release in cytosol, decreases heat shock protein (HSP) 70 and 90 expression, activates caspase-9, caspase-3, induces poly (ADP-ribose) polymerase (PARP) cleavage, and up-regulates caspase-3.

Below are the list of possible Bengalin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Bengalin

 Bengalin ELISA Kit
 Bengalin Recombinant
 Bengalin Antibody
Toxin that shows cardiotoxicity on isolated guinea pig heart and auricle and neurotoxicity on isolated rat phrenic nerve diaphragm. Shows antiosteoporosis activity in experimental rats. Also induces a
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poptosis against human leukemic cells (U937 and K562). Has no effect on normal human lymphocytes. Apoptosis has been evidenced from damaged nuclei, cell cycle arrest at sub G1 phase, increase of early apoptotic cells, augmentation of DNA fragmentation and also a reduction of telomerase activity. Also elicits loss of mitochondrial membrane potential (MMP) which induces cytochrome c release in cytosol, decreases heat shock protein (HSP) 70 and 90 expression, activates caspase-9, caspase-3, induces poly (ADP-ribose) polymerase (PARP) cleavage, and up-regulates caspase-3.
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