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Bestrophin

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Forms chloride channels.

Below are the list of possible Bestrophin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Bestrophin homolog 1

 Bestrophin homolog 1 ELISA Kit
 Bestrophin homolog 1 Recombinant
 Bestrophin homolog 1 Antibody
Forms chloride channels.
 best-1 ELISA Kit
 best-1 Recombinant
 best-1 Antibody
 B0564.3 ELISA Kit
 B0564.3 Recombinant
 B0564.3 Antibody
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Bestrophin homolog 12

 Bestrophin homolog 12 ELISA Kit
 Bestrophin homolog 12 Recombinant
 Bestrophin homolog 12 Antibody
Forms chloride channels.
 best-12 ELISA Kit
 best-12 Recombinant
 best-12 Antibody
 F14H3.2 ELISA Kit
 F14H3.2 Recombinant
 F14H3.2 Antibody
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Bestrophin homolog 13

 Bestrophin homolog 13 ELISA Kit
 Bestrophin homolog 13 Recombinant
 Bestrophin homolog 13 Antibody
Forms chloride channels.
 best-13 ELISA Kit
 best-13 Recombinant
 best-13 Antibody
 F32B6.9 ELISA Kit
 F32B6.9 Recombinant
 F32B6.9 Antibody
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Bestrophin homolog 14

 Bestrophin homolog 14 ELISA Kit
 Bestrophin homolog 14 Recombinant
 Bestrophin homolog 14 Antibody
 best-14 ELISA Kit
 best-14 Recombinant
 best-14 Antibody
 F32G8.4 ELISA Kit
 F32G8.4 Recombinant
 F32G8.4 Antibody
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Bestrophin homolog 15

 Bestrophin homolog 15 ELISA Kit
 Bestrophin homolog 15 Recombinant
 Bestrophin homolog 15 Antibody
Also known as Bestrophin homolog 15 (Bestrophin-1) (ceBest1).
Forms chloride channels.
 best-15 ELISA Kit
 best-15 Recombinant
 best-15 Antibody
 R13.3 ELISA Kit
 R13.3 Recombinant
 R13.3 Antibody
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Bestrophin homolog 17

 Bestrophin homolog 17 ELISA Kit
 Bestrophin homolog 17 Recombinant
 Bestrophin homolog 17 Antibody
Forms chloride channels.
 best-17 ELISA Kit
 best-17 Recombinant
 best-17 Antibody
 T19C3.1 ELISA Kit
 T19C3.1 Recombinant
 T19C3.1 Antibody
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Bestrophin homolog 18

 Bestrophin homolog 18 ELISA Kit
 Bestrophin homolog 18 Recombinant
 Bestrophin homolog 18 Antibody
Forms chloride channels.
 best-18 ELISA Kit
 best-18 Recombinant
 best-18 Antibody
 T20G5.4 ELISA Kit
 T20G5.4 Recombinant
 T20G5.4 Antibody
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Bestrophin homolog 2

 Bestrophin homolog 2 ELISA Kit
 Bestrophin homolog 2 Recombinant
 Bestrophin homolog 2 Antibody
Forms chloride channels.
 best-2 ELISA Kit
 best-2 Recombinant
 best-2 Antibody
 B0564.4 ELISA Kit
 B0564.4 Recombinant
 B0564.4 Antibody
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Bestrophin homolog 22

 Bestrophin homolog 22 ELISA Kit
 Bestrophin homolog 22 Recombinant
 Bestrophin homolog 22 Antibody
Forms chloride channels.
 best-22 ELISA Kit
 best-22 Recombinant
 best-22 Antibody
 ZC518.1 ELISA Kit
 ZC518.1 Recombinant
 ZC518.1 Antibody
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Bestrophin homolog 24

 Bestrophin homolog 24 ELISA Kit
 Bestrophin homolog 24 Recombinant
 Bestrophin homolog 24 Antibody
Forms chloride channels.
 best-24 ELISA Kit
 best-24 Recombinant
 best-24 Antibody
 ZK688.2 ELISA Kit
 ZK688.2 Recombinant
 ZK688.2 Antibody
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Bestrophin homolog 25

 Bestrophin homolog 25 ELISA Kit
 Bestrophin homolog 25 Recombinant
 Bestrophin homolog 25 Antibody
Forms chloride channels.
 best-25 ELISA Kit
 best-25 Recombinant
 best-25 Antibody
 ZK849.4 ELISA Kit
 ZK849.4 Recombinant
 ZK849.4 Antibody
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Bestrophin homolog 26

 Bestrophin homolog 26 ELISA Kit
 Bestrophin homolog 26 Recombinant
 Bestrophin homolog 26 Antibody
Forms chloride channels.
 best-26 ELISA Kit
 best-26 Recombinant
 best-26 Antibody
 ZK849.5 ELISA Kit
 ZK849.5 Recombinant
 ZK849.5 Antibody
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Bestrophin homolog 5

 Bestrophin homolog 5 ELISA Kit
 Bestrophin homolog 5 Recombinant
 Bestrophin homolog 5 Antibody
Forms chloride channels.
 best-5 ELISA Kit
 best-5 Recombinant
 best-5 Antibody
 C07A9.8 ELISA Kit
 C07A9.8 Recombinant
 C07A9.8 Antibody
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Bestrophin homolog 9

 Bestrophin homolog 9 ELISA Kit
 Bestrophin homolog 9 Recombinant
 Bestrophin homolog 9 Antibody
Forms chloride channels.
 best-9 ELISA Kit
 best-9 Recombinant
 best-9 Antibody
 C43G2.4 ELISA Kit
 C43G2.4 Recombinant
 C43G2.4 Antibody
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Bestrophin-1

 Bestrophin-1 ELISA Kit
 Bestrophin-1 Recombinant
 Bestrophin-1 Antibody
Also known as Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2).
BEST1: Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. Defects in BEST1 are the cause of vitelliform macular dystrophy type 2 (VMD2); also known as Best macular dystrophy (BMD). VMD2 is an autosomal dominant form of macular degeneration that usually begins in childhood or adolescence. VMD2
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is characterized by typical 'egg-yolk' macular lesions due to abnormal accumulation of lipofuscin within and beneath the retinal pigment epithelium cells. Progression of the disease leads to destruction of the retinal pigment epithelium and vision loss. Defects in BEST1 are the cause of retinitis pigmentosa type 50 (RP50). A retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Defects in BEST1 are a cause of adult-onset vitelliform macular dystrophy (AVMD). AVMD is a rare autosomal dominant disorder with incomplete penetrance and highly variable expression. Patients usually become symptomatic in the fourth or fifth decade of life with a protracted disease of decreased visual acuity. Defects in BEST1 are the cause of bestrophinopathy autosomal recessive (ARB). A retinopathy characterized by central visual loss, an absent electro-oculogram light rise, and a reduced electroretinogram. Defects in BEST1 are the cause of vitreoretinochoroidopathy autosomal dominant (ADVIRC). A disorder characterized by vitreoretinochoroidal dystrophy. The clinical presentation is variable and may be associated with cataract, nanophthalmos, microcornea, shallow anterior chamber, and glaucoma. Belongs to the bestrophin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, chloride; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: basolateral plasma membrane; cytosol; integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: bicarbonate transmembrane transporter activity; chloride channel activity; identical protein binding; intracellular calcium activated chloride channel activity

Biological Process: chloride transport; transepithelial chloride transport; visual perception

Disease: Bestrophinopathy, Autosomal Recessive; Macular Dystrophy, Vitelliform, 2; Retinitis Pigmentosa 50; Vitreoretinochoroidopathy
 BEST1 ELISA Kit
 BEST1 Recombinant
 BEST1 Antibody
 VMD2 ELISA Kit
 VMD2 Recombinant
 VMD2 Antibody
Table BarTOPTable Bar
 

Bestrophin-2

 Bestrophin-2 ELISA Kit
 Bestrophin-2 Recombinant
 Bestrophin-2 Antibody
Also known as Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).
BEST2: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Cellular Component: cilium; integral to plasma membrane

Molecular Function: chl
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oride channel activity

Biological Process: chloride transport; membrane depolarization; sensory perception of smell
 Best2 ELISA Kit
 Best2 Recombinant
 Best2 Antibody
 Vmd2l1 ELISA Kit
 Vmd2l1 Recombinant
 Vmd2l1 Antibody
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Bestrophin-3

 Bestrophin-3 ELISA Kit
 Bestrophin-3 Recombinant
 Bestrophin-3 Antibody
Also known as Bestrophin-3 (Vitelliform macular dystrophy 2-like protein 3).
VMD2L3: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ion channel

Cellular Component: integral
>>>
to plasma membrane

Molecular Function: chloride channel activity

Biological Process: inorganic anion transport; negative regulation of ion transport
 Best3 ELISA Kit
 Best3 Recombinant
 Best3 Antibody
 Vmd2l3 ELISA Kit
 Vmd2l3 Recombinant
 Vmd2l3 Antibody
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Bestrophin-4

 Bestrophin-4 ELISA Kit
 Bestrophin-4 Recombinant
 Bestrophin-4 Antibody
Also known as Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 2).
BEST4: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: integral to
>>>
plasma membrane

Molecular Function: chloride channel activity
 BEST4 ELISA Kit
 BEST4 Recombinant
 BEST4 Antibody
 VMD2L2 ELISA Kit
 VMD2L2 Recombinant
 VMD2L2 Antibody
Table BarTOPTable Bar
 

Bestrophin-6

 Bestrophin-6 ELISA Kit
 Bestrophin-6 Recombinant
 Bestrophin-6 Antibody
 best-6 ELISA Kit
 best-6 Recombinant
 best-6 Antibody
 C09B9.3 ELISA Kit
 C09B9.3 Recombinant
 C09B9.3 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
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