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Beta/kappa-theraphotoxin

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Below are the list of possible Beta/kappa-theraphotoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Beta/kappa-theraphotoxin-Cg1a

 Beta/kappa-theraphotoxin-Cg1a ELISA Kit
 Beta/kappa-theraphotoxin-Cg1a Recombinant
 Beta/kappa-theraphotoxin-Cg1a Antibody
Also known as Beta/kappa-theraphotoxin-Cg1a (Beta/kappa-TRTX-Cg1a) (Jingzhaotoxin-3) (Jingzhaotoxin-III) (JZTX-III) (Peptide F5-20.38).
Selectively inhibits activation of voltage-gated sodium chann
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els (VGSC) (Nav1.5/SCN5A) in rat cardiac myocytes, followed by shifting activated voltage in a depolarizing direction. The binding site on VGSC is suggested to be site 4 located at the extracellular S3-S4 loop of the channel. Also binds to voltage-gated potassium channels (Kv2.1/KCNB1).
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Beta/kappa-theraphotoxin-Cg2a

 Beta/kappa-theraphotoxin-Cg2a ELISA Kit
 Beta/kappa-theraphotoxin-Cg2a Recombinant
 Beta/kappa-theraphotoxin-Cg2a Antibody
Also known as Beta/kappa-theraphotoxin-Cg2a (Beta/kappa-TRTX-Cg2a) (Jingzhaotoxin-5) (Jingzhaotoxin-V) (JZTX-V) (Peptide F8-15.73).
Inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium
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channels (Nav) in rat dorsal root ganglion neurons. Highly inhibits Kv4.2/KCND2 and Kv4.3/KCND3 potassium channels and weakly inhibits Kv2.1/KCNB1 potassium channels. The toxin shifts the activation curves to more depolarized potentials. Also binds to phospholipid membranes.
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Beta/kappa-theraphotoxin-Hlv1a

 Beta/kappa-theraphotoxin-Hlv1a ELISA Kit
 Beta/kappa-theraphotoxin-Hlv1a Recombinant
 Beta/kappa-theraphotoxin-Hlv1a Antibody
Also known as Beta/kappa-theraphotoxin-Hlv1a (Beta/kappa-TRTX-Hlv1a) (Beta/kappa-theraphotoxin-Hl2a) (Beta/kappa-TRTX-Hl2a) (Haplotoxin-2).
Spider venom neurotoxin that blocks voltage-gated sodium
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channel Nav1.3/SCN3A in human (IC50=80 nM) and rat (IC50=160 nM). Partially inhibits human Kv11.1/KCNH2/ERG (25% at 175 µM).
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Beta/kappa-theraphotoxin-Pm2a

 Beta/kappa-theraphotoxin-Pm2a ELISA Kit
 Beta/kappa-theraphotoxin-Pm2a Recombinant
 Beta/kappa-theraphotoxin-Pm2a Antibody
Also known as Beta/kappa-theraphotoxin-Pm2a (Beta/kappa-TRTX-Pm2a) (Pterinotoxin-2).
Spider venom neurotoxin that blocks voltage-gated sodium channel Nav1.3/SCN3A in human (IC50=1 µM) and rat (IC5
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0=1 µM). Partially inhibits human Kv11.1/KCNH2/ERG (40% at 10 µM).
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