Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Beta/omega-theraphotoxin  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ABCG1 Antibody
 • TPD52L3 - D55 Peptide
 • HRP Conjugated Goat Anti-human IgM Secondary Antibody
 • 1,25-Dihydroxyvitamin D3 (DHVD3) ELISA Kit
 • Leptin ELISA Kit
 • Pulmonary Surfactant Associated Protein A (SPA) ELISA Kit
 • CD195 Antibody
 • HIV-1 gp120 Recombinant Protein
 • Annexin A2 (ANXA2) ELISA Kit
 • Chemokine interferon-inducible protein 10 (IP-10) ELISA Kit
 • IHOG Antibody
 • Enoyl-[acyl-carrier-protein ] reductase [NADH] FabI (fabI) Recombinant Protein
 • STK38L Antibody
 • Vitamin D Receptor (Phospho-Ser208) (VDR) Antibody
 downarrow more ...
separator

Beta/omega-theraphotoxin

separator
Inhibits voltage-gated calcium channels Cav3.1/CACNA1G, voltage-gated potassium channels Kv2.1/KCNB1 and all sodium channels tested (Nav1.2/SCN2A, Nav1.5/SCN5A, Nav1.7/SCN9A, and Nav1.8/SCN10A). Shifts the voltage-dependence of channel activation to more positive potentials. Most potent against Nav1.8/SCN10A.

Below are the list of possible Beta/omega-theraphotoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Beta/omega-theraphotoxin-Tp1a

 Beta/omega-theraphotoxin-Tp1a ELISA Kit
 Beta/omega-theraphotoxin-Tp1a Recombinant
 Beta/omega-theraphotoxin-Tp1a Antibody
Also known as Beta/omega-theraphotoxin-Tp1a (Beta/omega-TRTX-Tp1a) (Protoxin-1) (ProTx-1) (ProTx-I) (ProTx1).
Inhibits voltage-gated calcium channels Cav3.1/CACNA1G, voltage-gated potassium channel
>>>
s Kv2.1/KCNB1 and all sodium channels tested (Nav1.2/SCN2A, Nav1.5/SCN5A, Nav1.7/SCN9A, and Nav1.8/SCN10A). Shifts the voltage-dependence of channel activation to more positive potentials. Most potent against Nav1.8/SCN10A.
Table BarTOPTable Bar
 

Beta/omega-theraphotoxin-Tp2a

 Beta/omega-theraphotoxin-Tp2a ELISA Kit
 Beta/omega-theraphotoxin-Tp2a Recombinant
 Beta/omega-theraphotoxin-Tp2a Antibody
Also known as Beta/omega-theraphotoxin-Tp2a (Beta/omega-TRTX-Tp2a) (ProTx-II) (PT-II) (Protoxin-2) (ProTx-2) (ProTx2).
Blocks both tetrodotoxin-sensitive and tetrodotoxin-resistant human voltage-ga
>>>
ted sodium channels by shifting the voltage dependence of channel activation to more positive potentials. Inhibits Nav1.2/SCN2A, Nav1.3/SCN3A, Nav1.5/SCN5A, Nav1.6/SCN8A, Nav1.7/SCN9A, Nav1.8/SCN10A. Is significantly more potent against Nav1.7/SCN9A than the other Nav channel subtypes. Has no significant effect on Kv1.2/KCNA2, Kv1.3/KCNA3, Kv1.5/KCNA5, and Kv2.1/KCNB1 channels. Also inhibits Cav1.2/CACNA1C and Cav3.1/CACNA1G channels with an IC50 around 100 nM. Does not bind to the pharmacologically defined Nav channel sites 3 or 4. Neutralization of gating charges in the voltage sensor (S4) of domain II of Nav1.2/SCN2A prevents the effect of the toxin on gating current. Thus, it has been suggested that the toxin acts by trapping the voltage sensor of Nav channel domain II in the resting state, impeding outward gating movement of the IIS4 transmembrane segment of the channel. Binds to phospholipids.
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions