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Beta-secretase

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Below are the list of possible Beta-secretase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Beta-secretase

 Beta-secretase ELISA Kit
 Beta-secretase Recombinant
 Beta-secretase Antibody
 BACE ELISA Kit
 BACE Recombinant
 BACE Antibody
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Beta-secretase 1

 Beta-secretase 1 ELISA Kit
 Beta-secretase 1 Recombinant
 Beta-secretase 1 Antibody
Also known as Beta-secretase 1 (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2).
BACE: an integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Cleaves APP at the amino terminus of the A-beta peptide sequence, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated carboxy-terminal fragment which is later release by gamma-secretase. Four splice-variant isoforms have
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been described.

Protein type: EC 3.4.23.46; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 11q23.2-q23.3

Cellular Component: endoplasmic reticulum lumen; endosome; endosome membrane; Golgi apparatus; integral to plasma membrane; late endosome; multivesicular body; plasma membrane; trans-Golgi network

Molecular Function: aspartic-type endopeptidase activity; beta-amyloid binding; beta-aspartyl-peptidase activity; enzyme binding; peptidase activity; protein binding

Biological Process: beta-amyloid metabolic process; cellular protein metabolic process; membrane protein ectodomain proteolysis; protein catabolic process; proteolysis
 BACE1 ELISA Kit
 BACE1 Recombinant
 BACE1 Antibody
 BACE ELISA Kit
 BACE Recombinant
 BACE Antibody
 KIAA1149 ELISA Kit
 KIAA1149 Recombinant
 KIAA1149 Antibody
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Beta-secretase 2

 Beta-secretase 2 ELISA Kit
 Beta-secretase 2 Recombinant
 Beta-secretase 2 Antibody
Also known as Beta-secretase 2 (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-as.
BACE2: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later released by gamma-secretase. It has also been shown tha
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t it can cleave APP between residues 671 and 672. Belongs to the peptidase A1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.23.45; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: Golgi apparatus

Molecular Function: aspartic-type endopeptidase activity; beta-amyloid binding

Biological Process: beta-amyloid metabolic process; membrane protein ectodomain proteolysis; negative regulation of amyloid precursor protein biosynthetic process; protein catabolic process
 BACE2 ELISA Kit
 BACE2 Recombinant
 BACE2 Antibody
 AEPLC ELISA Kit
 AEPLC Recombinant
 AEPLC Antibody
 ALP56 ELISA Kit
 ALP56 Recombinant
 ALP56 Antibody
 ASP21 ELISA Kit
 ASP21 Recombinant
 ASP21 Antibody
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