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Beta-synuclein

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Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

Below are the list of possible Beta-synuclein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Beta-synuclein

 Beta-synuclein ELISA Kit
 Beta-synuclein Recombinant
 Beta-synuclein Antibody
SNCB: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May play a role in neuronal plasticity, is abundant in neurofibrillary lesions of Alzheimer's patients. Highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease.

Protein type: Adaptor/scaffold

Chromosomal
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Location of Human Ortholog: 5q35

Cellular Component: cytoplasm; Golgi apparatus; inclusion body; nucleoplasm

Molecular Function: calcium ion binding; phospholipase inhibitor activity

Disease: Dementia, Lewy Body
 SNCB ELISA Kit
 SNCB Recombinant
 SNCB Antibody
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