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Beta-toxin

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Below are the list of possible Beta-toxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Beta-toxin BmKAS

 Beta-toxin BmKAS ELISA Kit
 Beta-toxin BmKAS Recombinant
 Beta-toxin BmKAS Antibody
Also known as Beta-toxin BmKAS (BmK AS) (BmK-AS) (BmK-PL).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potenti
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als thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. It binds to distinct receptor sites of mammal and insect voltage-gated sodium channels. It displays antinociceptive effect in rat models, which is due to its specific modulation of sodium channels of sensory neurons. It also significantly stimulates the binding of [3H]-ryanodine to ryanodine receptors on the sarcoplasmic reticulum of the skeletal muscle through an indirect mechanism. And it promotes noradrenaline release from the rat hippocampus slice.
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Beta-toxin BmKAs1

 Beta-toxin BmKAs1 ELISA Kit
 Beta-toxin BmKAs1 Recombinant
 Beta-toxin BmKAs1 Antibody
Also known as Beta-toxin BmKAs1 (BmK AS-1) (BmK activator of skeletal-muscle ryanodine receptor) (Toxin BmP09).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift t
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he voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. BmKAs1 also significantly stimulates the binding of [3H]-ryanodine to ryanodine receptors on the sarcoplasmic reticulum of the skeletal muscle. It also displays antinociceptive effect in rat models.
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Beta-toxin BotIT2

 Beta-toxin BotIT2 ELISA Kit
 Beta-toxin BotIT2 Recombinant
 Beta-toxin BotIT2 Antibody
Also known as Beta-toxin BotIT2 (Bot IT2) (Insect toxin 2).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potent
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ials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin specifically acts by inducing a new current with very slow activation/deactivation kinetics due to the transformation of normal fast channels into slow ones. It possess properties of excitatory and depressant toxins. It is highly active on insects and less active on mammals.
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Beta-toxin CeII8

 Beta-toxin CeII8 ELISA Kit
 Beta-toxin CeII8 Recombinant
 Beta-toxin CeII8 Antibody
Beta toxins bind at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive f
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iring. Has a selective effect toward Nav1.7/SCN9A which plays a role in pain mechanisms, and especially in the development of inflammatory pain. Shows no lethality toward mice.
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Beta-toxin Cii1

 Beta-toxin Cii1 ELISA Kit
 Beta-toxin Cii1 Recombinant
 Beta-toxin Cii1 Antibody
Also known as Beta-toxin Cii1 (Cii 1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affectin
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g sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Cll1m

 Beta-toxin Cll1m ELISA Kit
 Beta-toxin Cll1m Recombinant
 Beta-toxin Cll1m Antibody
Also known as Beta-toxin Cll1m (Neurotoxin 1) (Toxin II.8.4.3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative po
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tentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Cll2

 Beta-toxin Cll2 ELISA Kit
 Beta-toxin Cll2 Recombinant
 Beta-toxin Cll2 Antibody
Also known as Beta-toxin Cll2 (Cll 2).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affectin
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g sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Clt1

 Beta-toxin Clt1 ELISA Kit
 Beta-toxin Clt1 Recombinant
 Beta-toxin Clt1 Antibody
Also known as Beta-toxin Clt1 (Neurotoxin 1) (Toxin II.20.3.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative po
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tentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Cn4

 Beta-toxin Cn4 ELISA Kit
 Beta-toxin Cn4 Recombinant
 Beta-toxin Cn4 Antibody
Also known as Beta-toxin Cn4 (Toxin 4) (Toxin CngtV) (Toxin II-10).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negativ
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e potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin affects the activation mechanism of sodium channels of squid axon. It also competes with Cn2 in rat brain synaptosomes. Is lethal to mice.
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Beta-toxin Cn5

 Beta-toxin Cn5 ELISA Kit
 Beta-toxin Cn5 Recombinant
 Beta-toxin Cn5 Antibody
Also known as Beta-toxin Cn5 (CngtII).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affectin
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g sodium channel activation and promoting spontaneous and repetitive firing. This toxin is lethal to crustaceans (freshwater crayfish (Cambarellus montezumae spp.)), it provokes a reversible paralysis to insects (crickets (Achaeta spp.)), but is not toxic to mice. At high concentrations, it does displace the (beta) mammal-specific toxin Cn2 from rat brain synaptosomes.
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Beta-toxin Cn7

 Beta-toxin Cn7 ELISA Kit
 Beta-toxin Cn7 Recombinant
 Beta-toxin Cn7 Antibody
Also known as Beta-toxin Cn7 (Toxin-7) (Toxin II-13.3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials
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thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Cn8

 Beta-toxin Cn8 ELISA Kit
 Beta-toxin Cn8 Recombinant
 Beta-toxin Cn8 Antibody
Also known as Beta-toxin Cn8 (Toxin-8) (Toxin II-13.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials
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thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Cn9

 Beta-toxin Cn9 ELISA Kit
 Beta-toxin Cn9 Recombinant
 Beta-toxin Cn9 Antibody
Also known as Beta-toxin Cn9 (Toxin-9) (Toxin II-14.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials
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thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin CsE3

 Beta-toxin CsE3 ELISA Kit
 Beta-toxin CsE3 Recombinant
 Beta-toxin CsE3 Antibody
Also known as Beta-toxin CsE3 (Neurotoxin E3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby
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affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin CsEI

 Beta-toxin CsEI ELISA Kit
 Beta-toxin CsEI Recombinant
 Beta-toxin CsEI Antibody
Also known as Beta-toxin CsEI (CsE-I) (Neurotoxin I).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials t
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hereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Affects channels from chicken and frog.
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Beta-toxin Css6

 Beta-toxin Css6 ELISA Kit
 Beta-toxin Css6 Recombinant
 Beta-toxin Css6 Antibody
Also known as Beta-toxin Css6 (Css VI) (CssVI).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby
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affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin Im-2

 Beta-toxin Im-2 ELISA Kit
 Beta-toxin Im-2 Recombinant
 Beta-toxin Im-2 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing (). Is toxic to both insect and mammals. Induces paralysis in Acheta domestica crickets, but does not induce death, whereas intracerebroventricular injection into mice causes immediate death (at a dose of 0.05 µg/g).
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Beta-toxin Isom1

 Beta-toxin Isom1 ELISA Kit
 Beta-toxin Isom1 Recombinant
 Beta-toxin Isom1 Antibody
Also known as Beta-toxin Isom1 (IsomTx1).
Excitatory insect beta-toxins induce a spastic paralysis (). They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of ac
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tivation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Beta-toxin KAaH1

 Beta-toxin KAaH1 ELISA Kit
 Beta-toxin KAaH1 Recombinant
 Beta-toxin KAaH1 Antibody
Also known as Beta-toxin KAaH1 (Peptide AaF1CA8).
Inhibits the vertebrate potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3 in vitro with an IC50 of 5.3 nM and 50.0 nM respectively.
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Beta-toxin KAaH2

 Beta-toxin KAaH2 ELISA Kit
 Beta-toxin KAaH2 Recombinant
 Beta-toxin KAaH2 Antibody
Also known as Beta-toxin KAaH2 (Peptide AaF1CA22).
Weakly inhibits the vertebrate potassium channel Kv1.1/KCNA1.
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Beta-toxin Tz1

 Beta-toxin Tz1 ELISA Kit
 Beta-toxin Tz1 Recombinant
 Beta-toxin Tz1 Antibody
Also known as Beta-toxin Tz1 (PT-beta NaTx14.1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereb
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y affecting sodium channel activation and promoting spontaneous and repetitive firing. Strongly affects skeletal muscle channels Nav1.4/SCN4A, poorly affects the neuronal channels Nav1.6/SCN8A and Nav1.2/SCN2A. Induces spastic paralysis of rear limbs, increased salivation, apnea, tachycardia and increased perspiration.
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