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Bifunctional helicase and thymine dioxygenase

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Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Probably also acts as a DNA helicase. Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis. Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis. In contrast to JBP1, it does not specifically bind DNA base J, it however binds chromatin (By similarity).

Below are the list of possible Bifunctional helicase and thymine dioxygenase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Bifunctional helicase and thymine dioxygenase JBP2

 Bifunctional helicase and thymine dioxygenase JBP2 ELISA Kit
 Bifunctional helicase and thymine dioxygenase JBP2 Recombinant
 Bifunctional helicase and thymine dioxygenase JBP2 Antibody
Also known as Bifunctional helicase and thymine dioxygenase JBP2 (J-binding protein 2).
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Probably also acts as a DNA helicase. Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J
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de novo synthesis. Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis. In contrast to JBP1, it does not specifically bind DNA base J, it however binds chromatin ().
 JBP2 ELISA Kit
 JBP2 Recombinant
 JBP2 Antibody
 LinJ14.0040 ELISA Kit
 LinJ14.0040 Recombinant
 LinJ14.0040 Antibody
 LinJ_14_0040 ELISA Kit
 LinJ_14_0040 Recombinant
 LinJ_14_0040 Antibody
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