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Bile acyl-CoA synthetase

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Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.

Below are the list of possible Bile acyl-CoA synthetase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Bile acyl-CoA synthetase

 Bile acyl-CoA synthetase ELISA Kit
 Bile acyl-CoA synthetase Recombinant
 Bile acyl-CoA synthetase Antibody
Also known as Bile acyl-CoA synthetase (BACS) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Fatty-acid-coenzyme A ligase, very long-chain 3) (Solute carrier family 27 member 5) (Very long-chai.
SLC27A5: Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic cir
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culation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Belongs to the ATP-dependent AMP-binding enzyme family.

Protein type: EC 6.2.1.7; Endoplasmic reticulum; Ligase; Lipid Metabolism - primary bile acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane

Molecular Function: long-chain-fatty-acid-CoA ligase activity; very-long-chain-fatty-acid-CoA ligase activity

Biological Process: bile acid and bile salt transport; bile acid biosynthetic process; very-long-chain fatty acid metabolic process
 SLC27A5 ELISA Kit
 SLC27A5 Recombinant
 SLC27A5 Antibody
 ACSB ELISA Kit
 ACSB Recombinant
 ACSB Antibody
 ACSVL6 ELISA Kit
 ACSVL6 Recombinant
 ACSVL6 Antibody
 FACVL3 ELISA Kit
 FACVL3 Recombinant
 FACVL3 Antibody
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