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Biotin--protein ligase

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Below are the list of possible Biotin--protein ligase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Biotin--protein ligase

 Biotin--protein ligase ELISA Kit
 Biotin--protein ligase Recombinant
 Biotin--protein ligase Antibody
Also known as Biotin--protein ligase (Biotin apo-protein ligase).
HLCS: Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase. Defects in HLCS are the cause of holocarboxylase synthetase deficiency (HLCS deficiency); also know
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n as biotin-responsive multiple carboxylase deficiency. HLCS deficiency is a neonatal form of multiple carboxylase deficiency, an autosomal recessive disorder characterized by metabolic ketoacidosis, hyperammonemia, excretion of abnormal organic acid metabolites and dermatitis. Clinical and biochemical symptoms improve dramatically with administration of biotin. Belongs to the biotin--protein ligase family.

Protein type: Cofactor and Vitamin Metabolism - biotin; EC 6.3.4.10; EC 6.3.4.11; EC 6.3.4.15; EC 6.3.4.9; Ligase; Mitochondrial

Cellular Component: chromatin; cytoplasm; cytosol; mitochondrion; nuclear lamina; nuclear matrix

Molecular Function: biotin binding; biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity; biotin-protein ligase activity; enzyme binding; protein homodimerization activity

Biological Process: cell proliferation; histone modification; protein amino acid biotinylation
 Hlcs ELISA Kit
 Hlcs Recombinant
 Hlcs Antibody
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Biotin--protein ligase 1

 Biotin--protein ligase 1 ELISA Kit
 Biotin--protein ligase 1 Recombinant
 Biotin--protein ligase 1 Antibody
Also known as Biotin--protein ligase 1, chloroplastic (Holocarboxylase synthetase 1).
Encodes a dual-targeted biotin holocarboxylase synthetase that can localize to the chloroplast and the cytosol. In vitro, it has been shown to catalyze the addition of biotin to the BCCP subunit of acetyl-CoA carboxylase and it can also biotinylate methylcrotonyl-CoA carboxylase. A small upstream ORF in the 5'UTR (uORF24) regulates the differential targeting of this enzyme.
 HCS1 ELISA Kit
 HCS1 Recombinant
 HCS1 Antibody
 At2g25710 ELISA Kit
 At2g25710 Recombinant
 At2g25710 Antibody
 F3N11.16 ELISA Kit
 F3N11.16 Recombinant
 F3N11.16 Antibody
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Biotin--protein ligase 2

 Biotin--protein ligase 2 ELISA Kit
 Biotin--protein ligase 2 Recombinant
 Biotin--protein ligase 2 Antibody
Also known as Biotin--protein ligase 2 (Holocarboxylase synthetase 2).
Although HCS2 is predicted to encode a biotin protein ligase / holocarboxylase synthetase (HCS), hcs2 mutants do not show a decrease in HCS activity. A dual-targeted HCS1 (At2g25710) might account for the HCS activity observed in multiple subcellular compartments in Arabidopsis.
 HCS2 ELISA Kit
 HCS2 Recombinant
 HCS2 Antibody
 At1g37150 ELISA Kit
 At1g37150 Recombinant
 At1g37150 Antibody
 F28L22.1 ELISA Kit
 F28L22.1 Recombinant
 F28L22.1 Antibody
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