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Brachyury protein

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Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.

Below are the list of possible Brachyury protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Brachyury protein

 Brachyury protein ELISA Kit
 Brachyury protein Recombinant
 Brachyury protein Antibody
Also known as Brachyury protein (Protein T).
Brachyury: Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called
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T site) and activates gene transcription when bound to such a site. Genetic variations in T are associated with susceptibility to neural tube defects (NTD). NTD are common congenital malformations. Spina bifida, which results from malformations in the caudal region of the neural tube, is compatible with life but associated with significant morbidity, including lower limb paralysis. T is involved in susceptibility to the development of chordoma (CHDM). Chordomas are rare, clinically malignant tumors derived from notochordal remnants. They occur along the length of the spinal axis, predominantly in the sphenooccipital, vertebral and sacrococcygeal regions. They are characterized by slow growth, local destruction of bone, extension into adjacent soft tissues and rarely, distant metastatic spread. Susceptibility to development of chordomas is due to a T gene duplication.

Protein type: Cell cycle regulation; DNA-binding; Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: nuclear chromatin; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding

Biological Process: determination of anterior/posterior axis, embryo; heart morphogenesis; mesoderm development; negative regulation of transcription from RNA polymerase II promoter

Disease: Neural Tube Defects; Sacral Agenesis With Vertebral Anomalies
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Brachyury protein homolog

 Brachyury protein homolog ELISA Kit
 Brachyury protein homolog Recombinant
 Brachyury protein homolog Antibody
Also known as Brachyury protein homolog (ApBra).
May be involved in the transcriptional regulation of genes required for gastrulation.
 Bra ELISA Kit
 Bra Recombinant
 Bra Antibody
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Brachyury protein homolog 1

 Brachyury protein homolog 1 ELISA Kit
 Brachyury protein homolog 1 Recombinant
 Brachyury protein homolog 1 Antibody
Also known as Brachyury protein homolog 1 (AmBra-1).
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.
 BRA-1 ELISA Kit
 BRA-1 Recombinant
 BRA-1 Antibody
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Brachyury protein homolog 2

 Brachyury protein homolog 2 ELISA Kit
 Brachyury protein homolog 2 Recombinant
 Brachyury protein homolog 2 Antibody
Also known as Brachyury protein homolog 2 (AmBra-2).
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.
 BRA-2 ELISA Kit
 BRA-2 Recombinant
 BRA-2 Antibody
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Brachyury protein homolog A

 Brachyury protein homolog A ELISA Kit
 Brachyury protein homolog A Recombinant
 Brachyury protein homolog A Antibody
Also known as Brachyury protein homolog A (No tail protein A) (No tail protein) (Protein T homolog A) (T-box protein ZfT) (Zf-T).
Involved in the transcriptional regulation of genes required for mesoderm differentiation, including itself. Indispensable for the formation of the notochord and the tail structure. Functions together with tbx16/spadetail in development of trunk and tail mesoderm. Fu
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nctions by itself early in development to repress medial floor plate and promote notochord fate but at later times, functions together with tbx16/spadetail to promote medial floor plate formation. Acts in a parallel pathway to, but cooperates with, non-canonical wnt-signaling during tail formation. Required for the morphogenesis of Kupffer's vesicle and regulates left-right asymmetry.
 ntla ELISA Kit
 ntla Recombinant
 ntla Antibody
 ntl ELISA Kit
 ntl Recombinant
 ntl Antibody
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