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Breast cancer metastasis-suppressor

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Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

Below are the list of possible Breast cancer metastasis-suppressor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Breast cancer metastasis-suppressor 1

 Breast cancer metastasis-suppressor 1 ELISA Kit
 Breast cancer metastasis-suppressor 1 Recombinant
 Breast cancer metastasis-suppressor 1 Antibody
BRMS1: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit meta
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stasis. May be a mediator of metastasis suppression in breast carcinoma. Belongs to the BRMS1 family.

Protein type: Tumor suppressor

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: histone deacetylase activity; histone deacetylase binding; NF-kappaB binding; protein binding

Biological Process: histone deacetylation; inhibition of NF-kappaB transcription factor; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
 BRMS1 ELISA Kit
 BRMS1 Recombinant
 BRMS1 Antibody
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Breast cancer metastasis-suppressor 1 homolog

 Breast cancer metastasis-suppressor 1 homolog ELISA Kit
 Breast cancer metastasis-suppressor 1 homolog Recombinant
 Breast cancer metastasis-suppressor 1 homolog Antibody
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (
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).
 BRMS1 ELISA Kit
 BRMS1 Recombinant
 BRMS1 Antibody
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