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C-myc promoter-binding protein

Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.

Below are the list of possible C-myc promoter-binding protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

C-myc promoter-binding protein

 C-myc promoter-binding protein ELISA Kit
 C-myc promoter-binding protein Recombinant
 C-myc promoter-binding protein Antibody
Also known as C-myc promoter-binding protein (DENN domain-containing protein 4A).
DENND4A: an ubiquitous nuclear guanine nucleotide exchange factor (GEF) that activates RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter. Highest expression in fetal liver, bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. Induced by serum in low-passage fibroblasts. Expressed at higher levels in normal cells (brain, breast, and
prostate) than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; GEFs; GEFs, Rab

Chromosomal Location of Human Ortholog: 15q22.31

Molecular Function: Rab guanyl-nucleotide exchange factor activity
 DENND4A Recombinant
 DENND4A Antibody
 IRLB Recombinant
 IRLB Antibody
 MYCPBP Recombinant
 MYCPBP Antibody
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