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C-type lectin domain family

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Below are the list of possible C-type lectin domain family products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

C-type lectin domain family 1 member A

 C-type lectin domain family 1 member A ELISA Kit
 C-type lectin domain family 1 member A Recombinant
 C-type lectin domain family 1 member A Antibody
CLEC1A:

Protein type: Membrane protein, integral
 Clec1a ELISA Kit
 Clec1a Recombinant
 Clec1a Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 1 member B

 C-type lectin domain family 1 member B ELISA Kit
 C-type lectin domain family 1 member B Recombinant
 C-type lectin domain family 1 member B Antibody
Also known as C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2).
CLEC1B: Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as
>>>
an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: integral to plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction; platelet formation
 Clec1b ELISA Kit
 Clec1b Recombinant
 Clec1b Antibody
 Clec2 ELISA Kit
 Clec2 Recombinant
 Clec2 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 10 member A

 C-type lectin domain family 10 member A ELISA Kit
 C-type lectin domain family 10 member A Recombinant
 C-type lectin domain family 10 member A Antibody
Also known as C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301).
CLEC10A: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1 >>>
>
Cellular Component: plasma membrane
 CLEC10A ELISA Kit
 CLEC10A Recombinant
 CLEC10A Antibody
 CLECSF13 ELISA Kit
 CLECSF13 Recombinant
 CLECSF13 Antibody
 CLECSF14 ELISA Kit
 CLECSF14 Recombinant
 CLECSF14 Antibody
 HML ELISA Kit
 HML Recombinant
 HML Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 11 member A

 C-type lectin domain family 11 member A ELISA Kit
 C-type lectin domain family 11 member A Recombinant
 C-type lectin domain family 11 member A Antibody
Also known as C-type lectin domain family 11 member A (C-type lectin superfamily member 3) (Lymphocyte secreted C-type lectin) (Stem cell growth factor) (p47).
CLEC11A: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.3
<
>>>
br>Cellular Component: extracellular region; extracellular space

Molecular Function: growth factor activity

Biological Process: positive regulation of cell proliferation
 CLEC11A ELISA Kit
 CLEC11A Recombinant
 CLEC11A Antibody
 CLECSF3 ELISA Kit
 CLECSF3 Recombinant
 CLECSF3 Antibody
 LSLCL ELISA Kit
 LSLCL Recombinant
 LSLCL Antibody
 SCGF ELISA Kit
 SCGF Recombinant
 SCGF Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 12 member A

 C-type lectin domain family 12 member A ELISA Kit
 C-type lectin domain family 12 member A Recombinant
 C-type lectin domain family 12 member A Antibody
Also known as C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL).
CLEC12A: Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.2
 CLEC12A ELISA Kit
 CLEC12A Recombinant
 CLEC12A Antibody
 CLL1 ELISA Kit
 CLL1 Recombinant
 CLL1 Antibody
 DCAL2 ELISA Kit
 DCAL2 Recombinant
 DCAL2 Antibody
 MICL ELISA Kit
 MICL Recombinant
 MICL Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 12 member B

 C-type lectin domain family 12 member B ELISA Kit
 C-type lectin domain family 12 member B Recombinant
 C-type lectin domain family 12 member B Antibody
CLEC12B: Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.
 Clec12b ELISA Kit
 Clec12b Recombinant
 Clec12b Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 14 member A

 C-type lectin domain family 14 member A ELISA Kit
 C-type lectin domain family 14 member A Recombinant
 C-type lectin domain family 14 member A Antibody
CLEC14A:

Protein type: Membrane protein, integral; Protease

Cellular Component: external side of plasma membrane; extracellular matrix

Biological Process: cell migration during sprouting angiogenesis
 Clec14a ELISA Kit
 Clec14a Recombinant
 Clec14a Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 17, member A

 C-type lectin domain family 17, member A ELISA Kit
 C-type lectin domain family 17, member A Recombinant
 C-type lectin domain family 17, member A Antibody
Also known as C-type lectin domain family 17, member A (Prolectin).
CLEC17A: Cell surface receptor which may be involved in carbohydrate-mediated communication between cells in the germinal center. Binds glycans with terminal alpha-linked mannose or fucose residues. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chrom
>>>
osomal Location of Human Ortholog: 19p13.12

Cellular Component: cell surface

Molecular Function: fucose binding; mannose binding
 CLEC17A ELISA Kit
 CLEC17A Recombinant
 CLEC17A Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 18 member A

 C-type lectin domain family 18 member A ELISA Kit
 C-type lectin domain family 18 member A Recombinant
 C-type lectin domain family 18 member A Antibody
Also known as C-type lectin domain family 18 member A (Mannose receptor-like protein 2).
CLEC18A: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: endoplasmic reticulum; endosome; extracellular space; Golgi apparatus

Molecular Func
>>>
tion: polysaccharide binding; protein binding
 CLEC18A ELISA Kit
 CLEC18A Recombinant
 CLEC18A Antibody
 MRLP2 ELISA Kit
 MRLP2 Recombinant
 MRLP2 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 18 member B

 C-type lectin domain family 18 member B ELISA Kit
 C-type lectin domain family 18 member B Recombinant
 C-type lectin domain family 18 member B Antibody
Also known as C-type lectin domain family 18 member B (Mannose receptor-like protein 1).
CLEC18B: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.3

Cellular Component: endosome; Golgi apparatus; sarcoplasmic reticulum
 CLEC18B ELISA Kit
 CLEC18B Recombinant
 CLEC18B Antibody
 MRLP1 ELISA Kit
 MRLP1 Recombinant
 MRLP1 Antibody
 UNQ306/PRO347 ELISA Kit
 UNQ306/PRO347 Recombinant
 UNQ306/PRO347 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 18 member C

 C-type lectin domain family 18 member C ELISA Kit
 C-type lectin domain family 18 member C Recombinant
 C-type lectin domain family 18 member C Antibody
Also known as C-type lectin domain family 18 member C (Mannose receptor-like protein 3).
CLEC18C: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: endoplasmic reticulum; endosome; Golgi apparatus

Molecular Function: polysaccharide
>>>
binding
 CLEC18C ELISA Kit
 CLEC18C Recombinant
 CLEC18C Antibody
 MRLP3 ELISA Kit
 MRLP3 Recombinant
 MRLP3 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 19 member A

 C-type lectin domain family 19 member A ELISA Kit
 C-type lectin domain family 19 member A Recombinant
 C-type lectin domain family 19 member A Antibody
CLEC19A:

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16p12.3
 CLEC19A ELISA Kit
 CLEC19A Recombinant
 CLEC19A Antibody
 UNQ5810/PRO19627 ELISA Kit
 UNQ5810/PRO19627 Recombinant
 UNQ5810/PRO19627 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member A

 C-type lectin domain family 2 member A ELISA Kit
 C-type lectin domain family 2 member A Recombinant
 C-type lectin domain family 2 member A Antibody
Also known as C-type lectin domain family 2 member A (Keratinocyte-associated C-type lectin) (KACL) (Proliferation-induced lymphocyte-associated receptor) (PILAR).
CLEC2A: Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti- apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity. 2
>>>
isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 12p13.31

Molecular Function: protein binding; protein homodimerization activity

Biological Process: natural killer cell mediated cytotoxicity
 CLEC2A ELISA Kit
 CLEC2A Recombinant
 CLEC2A Antibody
 KACL ELISA Kit
 KACL Recombinant
 KACL Antibody
 UNQ5792/PRO19597 ELISA Kit
 UNQ5792/PRO19597 Recombinant
 UNQ5792/PRO19597 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member B

 C-type lectin domain family 2 member B ELISA Kit
 C-type lectin domain family 2 member B Recombinant
 C-type lectin domain family 2 member B Antibody
Also known as C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1).
CLEC2B:

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13-p12

Cellular Component: integral to plasma membrane; plasma membrane

Biological Process: regulation of immune response
 CLEC2B ELISA Kit
 CLEC2B Recombinant
 CLEC2B Antibody
 AICL ELISA Kit
 AICL Recombinant
 AICL Antibody
 CLECSF2 ELISA Kit
 CLECSF2 Recombinant
 CLECSF2 Antibody
 IFNRG1 ELISA Kit
 IFNRG1 Recombinant
 IFNRG1 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member D

 C-type lectin domain family 2 member D ELISA Kit
 C-type lectin domain family 2 member D Recombinant
 C-type lectin domain family 2 member D Antibody
Also known as C-type lectin domain family 2 member D (C-type lectin-related protein B) (Clr-b) (Lectin-like transmembrane protein) (Osteoclast inhibitory lectin).
CLEC2D: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: external side of plasma membrane;
>>>
integral to plasma membrane

Molecular Function: carbohydrate binding; natural killer cell lectin-like receptor binding; protein binding; transmembrane receptor activity

Biological Process: cellular defense response; negative regulation of osteoclast differentiation; protection from natural killer cell mediated cytotoxicity
 Clec2d ELISA Kit
 Clec2d Recombinant
 Clec2d Antibody
 Clrb ELISA Kit
 Clrb Recombinant
 Clrb Antibody
 Ocil ELISA Kit
 Ocil Recombinant
 Ocil Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member D11

 C-type lectin domain family 2 member D11 ELISA Kit
 C-type lectin domain family 2 member D11 Recombinant
 C-type lectin domain family 2 member D11 Antibody
Also known as C-type lectin domain family 2 member D11 (C-type lectin-related protein B) (Clr-b) (Lectin-like transmembrane protein) (Osteoclast inhibitory lectin).
CLEC2G: Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis
 Clec2d11 ELISA Kit
 Clec2d11 Recombinant
 Clec2d11 Antibody
 Clrb ELISA Kit
 Clrb Recombinant
 Clrb Antibody
 Ocil ELISA Kit
 Ocil Recombinant
 Ocil Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member D2

 C-type lectin domain family 2 member D2 ELISA Kit
 C-type lectin domain family 2 member D2 Recombinant
 C-type lectin domain family 2 member D2 Antibody
Lectin-type cell surface receptor.
 Clec2d2 ELISA Kit
 Clec2d2 Recombinant
 Clec2d2 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member D3

 C-type lectin domain family 2 member D3 ELISA Kit
 C-type lectin domain family 2 member D3 Recombinant
 C-type lectin domain family 2 member D3 Antibody
Lectin-type cell surface receptor.
 Clec2d3 ELISA Kit
 Clec2d3 Recombinant
 Clec2d3 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member D5

 C-type lectin domain family 2 member D5 ELISA Kit
 C-type lectin domain family 2 member D5 Recombinant
 C-type lectin domain family 2 member D5 Antibody
Also known as C-type lectin domain family 2 member D5 (Osteoclast inhibitory lectin).
mouse homolog inhibits osteoclast formation [RGD, Feb 2006]
 Ocil ELISA Kit
 Ocil Recombinant
 Ocil Antibody
 Clec2d5 ELISA Kit
 Clec2d5 Recombinant
 Clec2d5 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member D6

 C-type lectin domain family 2 member D6 ELISA Kit
 C-type lectin domain family 2 member D6 Recombinant
 C-type lectin domain family 2 member D6 Antibody
Lectin-type cell surface receptor.
 Clec2d6 ELISA Kit
 Clec2d6 Recombinant
 Clec2d6 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member E

 C-type lectin domain family 2 member E ELISA Kit
 C-type lectin domain family 2 member E Recombinant
 C-type lectin domain family 2 member E Antibody
Also known as C-type lectin domain family 2 member E (C-type lectin-related protein A) (Clr-a).
CLEC2E: Lectin-type cell surface receptor.

Protein type: Membrane protein, anchored
 Clec2e ELISA Kit
 Clec2e Recombinant
 Clec2e Antibody
 Clra ELISA Kit
 Clra Recombinant
 Clra Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member F

 C-type lectin domain family 2 member F ELISA Kit
 C-type lectin domain family 2 member F Recombinant
 C-type lectin domain family 2 member F Antibody
Also known as C-type lectin domain family 2 member F (C-type lectin-related protein C) (Clr-c).
CLEC2F: Lectin-type cell surface receptor.

Protein type: Membrane protein, integral

Molecular Function: protein homodimerization activity
 Clec2f ELISA Kit
 Clec2f Recombinant
 Clec2f Antibody
 Clrc ELISA Kit
 Clrc Recombinant
 Clrc Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member G

 C-type lectin domain family 2 member G ELISA Kit
 C-type lectin domain family 2 member G Recombinant
 C-type lectin domain family 2 member G Antibody
Also known as C-type lectin domain family 2 member G (DDV10) (Osteoclast inhibitory lectin-related protein 1) (Ocil-related protein 1).
CLEC2G: Inhibits osteoclast formation. Constitutively expressed in bone marrow cells. Up-regulated in vagina after 17-beta-estradiol treatment. Down-regulated after removal of ovaries.

Cellular Component: extracellular space

Molecular Function: natural killer cell lectin-like receptor binding

Biological Process: negative regulation of osteoclast differentiation
 Clec2g ELISA Kit
 Clec2g Recombinant
 Clec2g Antibody
 Clec2f ELISA Kit
 Clec2f Recombinant
 Clec2f Antibody
 Ddv10 ELISA Kit
 Ddv10 Recombinant
 Ddv10 Antibody
 Ocilrp1 ELISA Kit
 Ocilrp1 Recombinant
 Ocilrp1 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member H

 C-type lectin domain family 2 member H ELISA Kit
 C-type lectin domain family 2 member H Recombinant
 C-type lectin domain family 2 member H Antibody
Also known as C-type lectin domain family 2 member H (C-type lectin-related protein F) (Clr-f).
CLEC2H:

Cellular Component: integral to plasma membrane

Molecular Function: carbohydrate binding; natural killer cell lectin-like receptor binding; transmembrane receptor activity

Biological Process: cellular defense response
 Clec2h ELISA Kit
 Clec2h Recombinant
 Clec2h Antibody
 Clrf ELISA Kit
 Clrf Recombinant
 Clrf Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member I

 C-type lectin domain family 2 member I ELISA Kit
 C-type lectin domain family 2 member I Recombinant
 C-type lectin domain family 2 member I Antibody
Also known as C-type lectin domain family 2 member I (C-type lectin-related protein DCL1) (C-type lectin-related protein G) (Clr-g) (Lymphoid-derived C-type lectin-1) (LCL-1) (Osteoclast inhibitory lectin-related protein 2) (Ocil-related protein 2).
CLEC2I:

Cellular Component: cell surface; external side of plasma membrane

Molecular Function: carbohydrate binding; natural killer cell lectin-like receptor binding; protein binding; transmembrane receptor activity

Biological Process: receptor clustering; regulation of actin filament polymerization; regulation of interleuk
>>>
in-2 biosynthetic process; regulation of T cell proliferation; T cell receptor signaling pathway
 Clec2i ELISA Kit
 Clec2i Recombinant
 Clec2i Antibody
 Clrg ELISA Kit
 Clrg Recombinant
 Clrg Antibody
 Dcl1 ELISA Kit
 Dcl1 Recombinant
 Dcl1 Antibody
 Ocilrp2 ELISA Kit
 Ocilrp2 Recombinant
 Ocilrp2 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 2 member L

 C-type lectin domain family 2 member L ELISA Kit
 C-type lectin domain family 2 member L Recombinant
 C-type lectin domain family 2 member L Antibody
CLEC2L:

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q34
 CLEC2L ELISA Kit
 CLEC2L Recombinant
 CLEC2L Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 3 member A

 C-type lectin domain family 3 member A ELISA Kit
 C-type lectin domain family 3 member A Recombinant
 C-type lectin domain family 3 member A Antibody
Also known as C-type lectin domain family 3 member A (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).
CLEC3A: Promotes cell adhesion to laminin-332 and fibronectin.

Protein type: Extracellular matrix; Secreted; Secreted, signal peptide
 Clec3a ELISA Kit
 Clec3a Recombinant
 Clec3a Antibody
 Clecsf1 ELISA Kit
 Clecsf1 Recombinant
 Clecsf1 Antibody
 Gm796 ELISA Kit
 Gm796 Recombinant
 Gm796 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 3 member A homolog

 C-type lectin domain family 3 member A homolog ELISA Kit
 C-type lectin domain family 3 member A homolog Recombinant
 C-type lectin domain family 3 member A homolog Antibody
Also known as C-type lectin domain family 3 member A homolog (C-type lectin superfamily member 1 homolog).
 clec3a ELISA Kit
 clec3a Recombinant
 clec3a Antibody
 clecsf1 ELISA Kit
 clecsf1 Recombinant
 clecsf1 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 4 member A

 C-type lectin domain family 4 member A ELISA Kit
 C-type lectin domain family 4 member A Recombinant
 C-type lectin domain family 4 member A Antibody
Also known as C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor).
CLEC4A: May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type:
>>>
Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: cell adhesion; cell surface receptor linked signal transduction; stimulatory C-type lectin receptor signaling pathway
 CLEC4A ELISA Kit
 CLEC4A Recombinant
 CLEC4A Antibody
 CLECSF6 ELISA Kit
 CLECSF6 Recombinant
 CLECSF6 Antibody
 DCIR ELISA Kit
 DCIR Recombinant
 DCIR Antibody
 LLIR ELISA Kit
 LLIR Recombinant
 LLIR Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 4 member C

 C-type lectin domain family 4 member C ELISA Kit
 C-type lectin domain family 4 member C Recombinant
 C-type lectin domain family 4 member C Antibody
Also known as C-type lectin domain family 4 member C (Blood dendritic cell antigen 2) (BDCA-2) (C-type lectin superfamily member 7) (Dendritic lectin) (CD antigen CD303).
CLEC4C: Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein- tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose. 2 isoforms of the human protein are produ
>>>
ced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 12p13.2-p12.3

Cellular Component: plasma membrane

Biological Process: stimulatory C-type lectin receptor signaling pathway
 CLEC4C ELISA Kit
 CLEC4C Recombinant
 CLEC4C Antibody
 BDCA2 ELISA Kit
 BDCA2 Recombinant
 BDCA2 Antibody
 CLECSF11 ELISA Kit
 CLECSF11 Recombinant
 CLECSF11 Antibody
 CLECSF7 ELISA Kit
 CLECSF7 Recombinant
 CLECSF7 Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 4 member D

 C-type lectin domain family 4 member D ELISA Kit
 C-type lectin domain family 4 member D Recombinant
 C-type lectin domain family 4 member D Antibody
Also known as C-type lectin domain family 4 member D (C-type lectin superfamily member 8).
human homolog may act as an endocytic receptor [RGD, Feb 2006]
 Clec4d ELISA Kit
 Clec4d Recombinant
 Clec4d Antibody
 Clecsf8 ELISA Kit
 Clecsf8 Recombinant
 Clecsf8 Antibody
 Mcl ELISA Kit
 Mcl Recombinant
 Mcl Antibody
Table BarTOPTable Bar
 

C-type lectin domain family 4 member E

 C-type lectin domain family 4 member E ELISA Kit
 C-type lectin domain family 4 member E Recombinant
 C-type lectin domain family 4 member E Antibody
Also known as C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).
CLEC4E: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by de
>>>
ad or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Protein type: Membrane protein, integral; Receptor, misc.

Molecular Function: receptor activity

Biological Process: defense response to bacterium; immune response; innate immune response; positive regulation of cytokine secretion; T cell differentiation during immune response
 Clec4e ELISA Kit
 Clec4e Recombinant
 Clec4e Antibody
 Clecsf9 ELISA Kit
 Clecsf9 Recombinant
 Clecsf9 Antibody
 Mincle ELISA Kit
 Mincle Recombinant
 Mincle Antibody
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C-type lectin domain family 4 member F

 C-type lectin domain family 4 member F ELISA Kit
 C-type lectin domain family 4 member F Recombinant
 C-type lectin domain family 4 member F Antibody
Also known as C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).
CLEC4F: Receptor with an affinity for galactose and fucose. Could be involved in endocytosis.

Protein type: Extracellular matrix; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p13.3
 CLEC4F ELISA Kit
 CLEC4F Recombinant
 CLEC4F Antibody
 CLECSF13 ELISA Kit
 CLECSF13 Recombinant
 CLECSF13 Antibody
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C-type lectin domain family 4 member G

 C-type lectin domain family 4 member G ELISA Kit
 C-type lectin domain family 4 member G Recombinant
 C-type lectin domain family 4 member G Antibody
CLEC4G: Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner, in vitro. {ECO:0000269|PubMed:14711836}

Protein type: Membrane protein, integral

Cellular Component: plasma membrane

Molecular Function: polysaccharide binding

Biological Process: negative regulation of T cell mediated immunity; negative regulation of T cell
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proliferation
 Clec4g ELISA Kit
 Clec4g Recombinant
 Clec4g Antibody
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C-type lectin domain family 4 member K

 C-type lectin domain family 4 member K ELISA Kit
 C-type lectin domain family 4 member K Recombinant
 C-type lectin domain family 4 member K Antibody
Also known as C-type lectin domain family 4 member K (Langerin) (CD antigen CD207).
langerin: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and
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is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. Homotrimer. Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 2p13

Cellular Component: early endosome membrane; endocytic vesicle; plasma membrane

Molecular Function: carbohydrate binding; mannose binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; defense response to virus; receptor-mediated endocytosis

Disease: Birbeck Granule Deficiency
 CD207 ELISA Kit
 CD207 Recombinant
 CD207 Antibody
 CLEC4K ELISA Kit
 CLEC4K Recombinant
 CLEC4K Antibody
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C-type lectin domain family 4 member M

 C-type lectin domain family 4 member M ELISA Kit
 C-type lectin domain family 4 member M Recombinant
 C-type lectin domain family 4 member M Antibody
Also known as C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299).
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety
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of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates ().
 CLEC4M ELISA Kit
 CLEC4M Recombinant
 CLEC4M Antibody
 CD209L1 ELISA Kit
 CD209L1 Recombinant
 CD209L1 Antibody
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C-type lectin domain family 5 member A

 C-type lectin domain family 5 member A ELISA Kit
 C-type lectin domain family 5 member A Recombinant
 C-type lectin domain family 5 member A Antibody
Also known as C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin 1) (MDL-1).
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation ().
 CLEC5A ELISA Kit
 CLEC5A Recombinant
 CLEC5A Antibody
 CLECSF5 ELISA Kit
 CLECSF5 Recombinant
 CLECSF5 Antibody
 MDL1 ELISA Kit
 MDL1 Recombinant
 MDL1 Antibody
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C-type lectin domain family 6 member A

 C-type lectin domain family 6 member A ELISA Kit
 C-type lectin domain family 6 member A Recombinant
 C-type lectin domain family 6 member A Antibody
Binds high-mannose carbohydrates in a Ca2+-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements f
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rom the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway ().
 CLEC6A ELISA Kit
 CLEC6A Recombinant
 CLEC6A Antibody
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C-type lectin domain family 7 member A

 C-type lectin domain family 7 member A ELISA Kit
 C-type lectin domain family 7 member A Recombinant
 C-type lectin domain family 7 member A Antibody
Also known as C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1).
dectin-1: Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in t
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he cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. Up-regulated during differentiation from monocytes into dendritic cells. Isoform 5 interacts with RANBP9. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral
 Clec7a ELISA Kit
 Clec7a Recombinant
 Clec7a Antibody
 Bgr ELISA Kit
 Bgr Recombinant
 Bgr Antibody
 Clecsf12 ELISA Kit
 Clecsf12 Recombinant
 Clecsf12 Antibody
 Dectin1 ELISA Kit
 Dectin1 Recombinant
 Dectin1 Antibody
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C-type lectin domain family 9 member A

 C-type lectin domain family 9 member A ELISA Kit
 C-type lectin domain family 9 member A Recombinant
 C-type lectin domain family 9 member A Antibody
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-depen
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dent manner ().
 Clec9a ELISA Kit
 Clec9a Recombinant
 Clec9a Antibody
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Proteins Root Name Listing
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