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C-type mannose receptor

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May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Below are the list of possible C-type mannose receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

C-type mannose receptor 2

 C-type mannose receptor 2 ELISA Kit
 C-type mannose receptor 2 Recombinant
 C-type mannose receptor 2 Antibody
Also known as C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280).
MRC2: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the ext
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racellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix co-operating with the matrix metalloproteinases (MMPs).

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q23.2

Cellular Component: focal adhesion; integral to plasma membrane; membrane

Molecular Function: collagen binding; protein binding; transmembrane receptor activity

Biological Process: collagen catabolic process; osteoblast differentiation
 MRC2 ELISA Kit
 MRC2 Recombinant
 MRC2 Antibody
 CLEC13E ELISA Kit
 CLEC13E Recombinant
 CLEC13E Antibody
 ENDO180 ELISA Kit
 ENDO180 Recombinant
 ENDO180 Antibody
 KIAA0709 ELISA Kit
 KIAA0709 Recombinant
 KIAA0709 Antibody
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